ID M2XXV9_GALSU Unreviewed; 365 AA.
AC M2XXV9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DNA repair protein RAD51 homolog {ECO:0000256|RuleBase:RU364139};
GN ORFNames=Gasu_42740 {ECO:0000313|EMBL:EME28274.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME28274.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- FUNCTION: Binds to single and double-stranded DNA and exhibits DNA-
CC dependent ATPase activity. Underwinds duplex DNA.
CC {ECO:0000256|RuleBase:RU364139}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364139}. Plastid, chloroplast
CC {ECO:0000256|ARBA:ARBA00004229}.
CC -!- SIMILARITY: Belongs to the RecA family. RAD51 subfamily.
CC {ECO:0000256|ARBA:ARBA00007095, ECO:0000256|RuleBase:RU364139}.
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DR EMBL; KB454522; EME28274.1; -; Genomic_DNA.
DR RefSeq; XP_005704794.1; XM_005704737.1.
DR AlphaFoldDB; M2XXV9; -.
DR SMR; M2XXV9; -.
DR STRING; 130081.M2XXV9; -.
DR EnsemblPlants; EME28274; EME28274; Gasu_42740.
DR GeneID; 17087127; -.
DR Gramene; EME28274; EME28274; Gasu_42740.
DR KEGG; gsl:Gasu_42740; -.
DR eggNOG; KOG1433; Eukaryota.
DR OMA; IHVARAY; -.
DR OrthoDB; 5477610at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005694; C:chromosome; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR GO; GO:0003690; F:double-stranded DNA binding; IEA:InterPro.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IEA:EnsemblPlants.
DR GO; GO:1990426; P:mitotic recombination-dependent replication fork processing; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:EnsemblPlants.
DR GO; GO:0010332; P:response to gamma radiation; IEA:EnsemblPlants.
DR CDD; cd19513; Rad51; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011941; DNA_recomb/repair_Rad51.
DR InterPro; IPR013632; DNA_recomb/repair_Rad51_C.
DR InterPro; IPR016467; DNA_recomb/repair_RecA-like.
DR InterPro; IPR010995; DNA_repair_Rad51/TF_NusA_a-hlx.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020588; RecA_ATP-bd.
DR InterPro; IPR020587; RecA_monomer-monomer_interface.
DR NCBIfam; TIGR02239; recomb_RAD51; 1.
DR PANTHER; PTHR22942:SF39; DNA REPAIR PROTEIN RAD51 HOMOLOG 1; 1.
DR PANTHER; PTHR22942; RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF08423; Rad51; 1.
DR PIRSF; PIRSF005856; Rad51; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47794; Rad51 N-terminal domain-like; 1.
DR PROSITE; PS50162; RECA_2; 1.
DR PROSITE; PS50163; RECA_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU003422};
KW DNA damage {ECO:0000256|RuleBase:RU364139};
KW DNA recombination {ECO:0000256|RuleBase:RU364139};
KW DNA repair {ECO:0000256|RuleBase:RU364139};
KW DNA-binding {ECO:0000256|RuleBase:RU364139};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003422};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364139};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 124..295
FT /note="RecA family profile 1"
FT /evidence="ECO:0000259|PROSITE:PS50162"
FT DOMAIN 302..365
FT /note="RecA family profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50163"
SQ SEQUENCE 365 AA; 40092 MW; C471AA28BFB0F838 CRC64;
MRICRRAIPT FIQICIWSSI SHNQAAMSKS LLQEPIKSEE DSEEFLGPLA IQKLEQVGIS
STDIKKLQDA GYHTIESVAY TTKKTLLDVK GISEAKAEKI INECAKLVNM GFTTAYEYHK
TRQEIISLTT GSQELDNLLA GGIETGSITE LFGEFRTGKT QLCHTLCVTC QLPIENGGGE
GKALYIDSEG TFRPERIVAI SERYGLNSED VLNNIAVARA YNSDHQLQLL TQACALMAES
RYALIIVDSA TALYRTDYSG RGELAARQQH MARFLRALQK LADEFGVAVV ITNQVVAQVD
GGAMFAVDPK KPIGGNIIAH ASQTRLYLRK GRAENRICKI YDSPCLPEAE ATFSIMADGI
RDASD
//
