ID M2XYP5_GALSU Unreviewed; 413 AA.
AC M2XYP5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 08-NOV-2023, entry version 41.
DE SubName: Full=AP-1 complex subunit mu isoform 1 {ECO:0000313|EMBL:EME28604.1};
GN ORFNames=Gasu_39800 {ECO:0000313|EMBL:EME28604.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME28604.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- SIMILARITY: Belongs to the adaptor complexes medium subunit family.
CC {ECO:0000256|PIRNR:PIRNR005992}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB454518; EME28604.1; -; Genomic_DNA.
DR RefSeq; XP_005705124.1; XM_005705067.1.
DR AlphaFoldDB; M2XYP5; -.
DR EnsemblPlants; EME28604; EME28604; Gasu_39800.
DR GeneID; 17087463; -.
DR Gramene; EME28604; EME28604; Gasu_39800.
DR KEGG; gsl:Gasu_39800; -.
DR OrthoDB; 6959at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0030131; C:clathrin adaptor complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd09250; AP-1_Mu1_Cterm; 1.
DR CDD; cd14835; AP1_Mu_N; 1.
DR Gene3D; 3.30.450.60; -; 1.
DR Gene3D; 2.60.40.1170; Mu homology domain, subdomain B; 2.
DR InterPro; IPR036168; AP2_Mu_C_sf.
DR InterPro; IPR022775; AP_mu_sigma_su.
DR InterPro; IPR001392; Clathrin_mu.
DR InterPro; IPR018240; Clathrin_mu_CS.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR028565; MHD.
DR PANTHER; PTHR10529:SF262; ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT; 1.
DR PANTHER; PTHR10529; AP COMPLEX SUBUNIT MU; 1.
DR Pfam; PF00928; Adap_comp_sub; 1.
DR Pfam; PF01217; Clat_adaptor_s; 1.
DR PIRSF; PIRSF005992; Clathrin_mu; 1.
DR PRINTS; PR00314; CLATHRINADPT.
DR SUPFAM; SSF49447; Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor; 1.
DR SUPFAM; SSF64356; SNARE-like; 1.
DR PROSITE; PS00990; CLAT_ADAPTOR_M_1; 1.
DR PROSITE; PS00991; CLAT_ADAPTOR_M_2; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|PIRNR:PIRNR005992};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005992}.
FT DOMAIN 167..413
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
SQ SEQUENCE 413 AA; 47317 MW; 09BE3053DDCB4EE1 CRC64;
MVSALYILDA RGRVLISRNY RGDVPVDVIS QVKLKVIEAE DDSSTKPILH DEQRGYSLAF
IKVADIFLVA VTRTNANAAL MLSFLYRVVL VFREYFKDVE EESIRDNFVL IYELLDEMMD
FGFPQSTESK VLQEYITQER HVLESPRPPI AVTNAVSWRS EGVKHQRNEV FLDVIEKVNL
LVGANGNLLY SEILGQMKMK SYLSGMPELK LGLNDKLQFE ATGRPGQGRA VELEDIKFHQ
CVRLSRFETD RTISFIPPDG EFELMSYRLS TPMRPLIWVD AMIEFHPYRV NYTINVRAQF
KPKYTANSVK IHIPTPPDAD TPSFKSASGR VKYTPEKDVV VWSLKHLHGG QELVVRGYFG
LPSIPSSENR EQAVRRPISV EFEIPYFTVS GLQVRYLKII EKSGYRALPW ITN
//
