ID M2Y4Q6_GALSU Unreviewed; 775 AA.
AC M2Y4Q6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=NADPH oxidase {ECO:0000313|EMBL:EME30933.1};
GN ORFNames=Gasu_17010 {ECO:0000313|EMBL:EME30933.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME30933.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
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DR EMBL; KB454495; EME30933.1; -; Genomic_DNA.
DR RefSeq; XP_005707453.1; XM_005707396.1.
DR AlphaFoldDB; M2Y4Q6; -.
DR STRING; 130081.M2Y4Q6; -.
DR TCDB; 5.B.1.1.11; the phagocyte (gp91(phox)) nadph oxidase family.
DR EnsemblPlants; EME30933; EME30933; Gasu_17010.
DR GeneID; 17089628; -.
DR Gramene; EME30933; EME30933; Gasu_17010.
DR KEGG; gsl:Gasu_17010; -.
DR eggNOG; KOG0039; Eukaryota.
DR OMA; ENACACA; -.
DR OrthoDB; 5489970at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 2.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972:SF69; METALLOREDUCTASE AIM14-RELATED; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 249..373
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 775 AA; 87155 MW; 02C77A655B083163 CRC64;
MTKAFYKRAS VTGNNSYRGS KDSNRFDSFL KLEAFMVNNG MLWTLLLFIA CMDIIGFLAG
VFNMITATQQ HIITIPFLER SLPVAKGAGR VISINAALLL LTGCKATITW LRSTFVSCLL
PIDKLMPFLH IRLYLIIAFC AALHAITQYV NYITGSFPWV FGLWTYHFPD PTVQLLITGT
LLVILMTAIA VTAGPWIRRS VNRGYNIFWT VHIVGFSCVY PLLILHGVLL GTPDTWKYIL
GPLVLYVIDV LYRARAVSFK GLSVVCWLNP SSEGVTELVM KRPFAYKAGQ YVQIRIPVVS
RWEYHPLSIA SAPHEEYLRI FIKSSGDWSS LVYKVSEELQ SDSFAFSDAA SQVDARGFTI
VNVRGPFGAP TEHVKDFSKV VLVGTGIGAT PFSSVVREYL HANSKEDQAA KRVHQTVLNL
SQLEKPSSAL VKDTKDHNNN SPSLRKVETL LPSFFMNMTQ LAYRGIVDPF LVFFKRTSIS
FKSENACACA FLGFFHSLSL NFMVLWMMMI AGSIRVAFVL FGYHGQYSSA IWGLVVSVII
LFVFGFSLFI AIRSLGWKYW KTAIGVLDSL AFFIGLALFI CVFVCIASWG TKSVWTIEKV
LNYLTFYCLI PVVGIRALLL IVNGCGGFKW KRSAKSNLKT ECSKSLHFIW VSRTVHGFHW
FFRDFERIVS EGSSVQVQMD IFVTGVTSDI TLPENSSKIR YHIGRPQWDS LFSSMFESEE
FIRDQEPVGV FFCGAPAVGR IVKAAANEAS LQAARRQYVT GNRCFPKIIF HKEYF
//
