ID M2Y4U2_GALSU Unreviewed; 729 AA.
AC M2Y4U2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=DEAD box protein 1 {ECO:0000256|ARBA:ARBA00032348};
GN ORFNames=Gasu_17500 {ECO:0000313|EMBL:EME30988.1};
OS Galdieria sulphuraria (Red alga).
OC Eukaryota; Rhodophyta; Bangiophyceae; Galdieriales; Galdieriaceae;
OC Galdieria.
OX NCBI_TaxID=130081 {ECO:0000313|EMBL:EME30988.1, ECO:0000313|Proteomes:UP000030680};
RN [1] {ECO:0000313|Proteomes:UP000030680}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=074W {ECO:0000313|Proteomes:UP000030680};
RX PubMed=23471408; DOI=10.1126/science.1231707;
RA Schonknecht G., Chen W.H., Ternes C.M., Barbier G.G., Shrestha R.P.,
RA Stanke M., Brautigam A., Baker B.J., Banfield J.F., Garavito R.M., Carr K.,
RA Wilkerson C., Rensing S.A., Gagneul D., Dickenson N.E., Oesterhelt C.,
RA Lercher M.J., Weber A.P.;
RT "Gene transfer from bacteria and archaea facilitated evolution of an
RT extremophilic eukaryote.";
RL Science 339:1207-1210(2013).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX1 subfamily.
CC {ECO:0000256|ARBA:ARBA00008765}.
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DR EMBL; KB454495; EME30988.1; -; Genomic_DNA.
DR RefSeq; XP_005707508.1; XM_005707451.1.
DR AlphaFoldDB; M2Y4U2; -.
DR STRING; 130081.M2Y4U2; -.
DR EnsemblPlants; EME30988; EME30988; Gasu_17500.
DR GeneID; 17089677; -.
DR Gramene; EME30988; EME30988; Gasu_17500.
DR KEGG; gsl:Gasu_17500; -.
DR eggNOG; KOG0349; Eukaryota.
DR OMA; EYCIRAI; -.
DR OrthoDB; 102545at2759; -.
DR Proteomes; UP000030680; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR CDD; cd12873; SPRY_DDX1; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EME30988.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030680}.
FT DOMAIN 2..30
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 55..241
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 275..416
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 479..673
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT MOTIF 2..30
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
SQ SEQUENCE 729 AA; 81786 MW; DC8330FCCD0ECA95 CRC64;
MSAFEELGVL PEIIKAVEDL DWSLPTPVQA ETIPLVLGGG DAMVSAETGS GKTGAFCLPL
VQVCYETLQG KFLQITKQPN HNDKSTSLWF KSDYNLIIDR EQTELENKLP NRWQGARASL
GANNGRWYFE VKVLSDGLCR VGWATEECSL DLGTDSEGLG YGGTGKKSHN REFANYGEPY
GEGDIIGCFI DFEESRLFFS KNGTILQTAF EIPAALKNCT FYPSVCLKKC RVQVNFGPVS
SKNFMDSFRM ISESPLCIEK TYSTGDSSKR KKNRRGPLAL ILEPSRELAL QVKEEIGKFS
KYLSPTIRCA CLVGGEKISQ NIHALDNGVE VVCGTLGRIQ ECIEGGHLVL SSLRFLVLDE
ADAFLHQNQM ESIIGIYSRV EEQNLVGGVQ VLFFSATLHS PEVHELSEKI QQSPMVVDMK
GRDYVPEEVE HSVFFVDPSQ NTTDSKDFSV HTDGVHEPEG QSTLEEWSSQ RIKQMKTVLV
RKLIESFSME QALIFVRTQL DADNLHHYLK NISLRNKSGY GKDERYSSVV LHGGISARER
KANLQNFKSG EARFLICTDV AARGIDVEGV PYLINVTLPD NVETYVHRVG RVGRSERLGL
AISLVGTKPE KVWFHRCPSR GRNNQCKNRR LLSEGGCTIW YDEMEIFKQI QKHLSLQVIT
LDSSFQLPVD NRKHFGYQSK EMEAIAAIQK KVDCLKPITT AVIELEDQVQ KNFLALSHRF
SLNHFNFCS
//
