ID M2ZHJ6_PSEFD Unreviewed; 464 AA.
AC M2ZHJ6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Probable kinetochore protein NUF2 {ECO:0000256|ARBA:ARBA00017594};
GN ORFNames=MYCFIDRAFT_31321 {ECO:0000313|EMBL:EME78609.1};
OS Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS fungus) (Mycosphaerella fijiensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=383855 {ECO:0000313|EMBL:EME78609.1, ECO:0000313|Proteomes:UP000016932};
RN [1] {ECO:0000313|EMBL:EME78609.1, ECO:0000313|Proteomes:UP000016932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRAD86 {ECO:0000313|EMBL:EME78609.1,
RC ECO:0000313|Proteomes:UP000016932};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- FUNCTION: Acts as a component of the essential kinetochore-associated
CC NDC80 complex, which is required for chromosome segregation and spindle
CC checkpoint activity. {ECO:0000256|ARBA:ARBA00002772}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NUF2 family.
CC {ECO:0000256|ARBA:ARBA00005498}.
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DR EMBL; KB446563; EME78609.1; -; Genomic_DNA.
DR RefSeq; XP_007930485.1; XM_007932294.1.
DR AlphaFoldDB; M2ZHJ6; -.
DR STRING; 383855.M2ZHJ6; -.
DR GeneID; 19338795; -.
DR KEGG; pfj:MYCFIDRAFT_31321; -.
DR eggNOG; KOG4438; Eukaryota.
DR HOGENOM; CLU_025461_2_1_1; -.
DR OrthoDB; 7316at2759; -.
DR Proteomes; UP000016932; Unassembled WGS sequence.
DR GO; GO:0031262; C:Ndc80 complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.10.418.60; Ncd80 complex, Nuf2 subunit; 1.
DR InterPro; IPR005549; Kinetochore_Nuf2_N.
DR InterPro; IPR041112; Nuf2_DHR10-like.
DR InterPro; IPR038275; Nuf2_N_sf.
DR PANTHER; PTHR21650:SF2; KINETOCHORE PROTEIN NUF2; 1.
DR PANTHER; PTHR21650; MEMBRALIN/KINETOCHORE PROTEIN NUF2; 1.
DR Pfam; PF03800; Nuf2; 1.
DR Pfam; PF18595; Nuf2_DHR10-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000016932}.
FT DOMAIN 29..170
FT /note="Kinetochore protein Nuf2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03800"
FT DOMAIN 282..397
FT /note="Nuf2 DHR10-like"
FT /evidence="ECO:0000259|Pfam:PF18595"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 169..238
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 316..452
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 464 AA; 54630 MW; 2ADEB91AD6584609 CRC64;
MDYNPRMSMA GGRSVSSQQK KQKEHDDGDA FMTLPDKEIA GCISDIGINF TVEDLRKPNP
QQIQKVFEWF AELLTNTTRE VVAPAMRAAA EDMCGDDAER IFTADTRELM GFFVTMRKLL
LECGIKDFTF SDLYRPTHPR LVKIFSYIIN FIRFRESQTA VIDEHYNSSE RVKNQIEQLY
HANQEKEDRL DEMQQNRKNV EAELQHKEQK SQELKTRLLE LKKTQERVTE KLERVKGEQS
RLKSLLEDKT TQVMQTRNEA SKLRPYAEQS PAHLEQSLRD LSTSLAADRS EIDRLDKRSR
ALQTSCDTFT LLQTDISSLT RLLSDLQSEL QKEDEEMRAA TKNREALTEK SNNVREVERQ
EKMLRKQLQQ WQDRTEKLRK DAEMRANNAK SKMEALRVTH RELTAERRER GEEVEKRRVR
IEQTEKKMAD LKEQIEHEVQ AAREEYMKME SHIRLYITEM EQSI
//
