ID M2ZP03_PSEFD Unreviewed; 790 AA.
AC M2ZP03;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=O-acyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=MYCFIDRAFT_208180 {ECO:0000313|EMBL:EME80819.1};
OS Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS fungus) (Mycosphaerella fijiensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=383855 {ECO:0000313|EMBL:EME80819.1, ECO:0000313|Proteomes:UP000016932};
RN [1] {ECO:0000313|EMBL:EME80819.1, ECO:0000313|Proteomes:UP000016932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRAD86 {ECO:0000313|EMBL:EME80819.1,
RC ECO:0000313|Proteomes:UP000016932};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- FUNCTION: Sterol O-acyltransferase that catalyzes the formation of
CC stery esters. {ECO:0000256|ARBA:ARBA00023568}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the membrane-bound acyltransferase family.
CC Sterol o-acyltransferase subfamily. {ECO:0000256|ARBA:ARBA00009010}.
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DR EMBL; KB446560; EME80819.1; -; Genomic_DNA.
DR RefSeq; XP_007928193.1; XM_007930002.1.
DR AlphaFoldDB; M2ZP03; -.
DR STRING; 383855.M2ZP03; -.
DR GeneID; 19336655; -.
DR KEGG; pfj:MYCFIDRAFT_208180; -.
DR eggNOG; KOG0380; Eukaryota.
DR HOGENOM; CLU_018190_2_1_1; -.
DR OrthoDB; 9612at2759; -.
DR Proteomes; UP000016932; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR InterPro; IPR004299; MBOAT_fam.
DR InterPro; IPR014371; Oat_ACAT_DAG_ARE.
DR PANTHER; PTHR10408; STEROL O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR10408:SF9; STEROL O-ACYLTRANSFERASE 1-RELATED; 1.
DR Pfam; PF03062; MBOAT; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016932};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 288..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 763..782
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 127..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 181..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..467
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 790 AA; 91047 MW; B7B60BC74D7DA94A CRC64;
MFFTFFLNSR HRWRVRRRFY IGISTGARAG SWGSGKWRGS TPRLAWSSAL VSRVKRQHPC
PRCGTMTARH THASTCIRPA LPNKDTLDVA RLTGTLGHNG VAELPPGSPK SNKNASLNAS
LARYPQSVQG TSDSFGHSVS LPQSDDSAVS SDIDDAIENY DQLQLDPDTL ILNTRRSLDE
AYRPSNSKME GKEQNGEQEE SASEAKRGHK KRNSIQIRLA RTDRKGKYIL TADDPEIKAI
LRKGIEREAE EAEGKIKKPP RINFRDLVFT RRFTTFDRQN PASADSPFFG FFTLFWICMF
LIFFQVALRN WRDYGSWLGG NQIMRMMFTR DVFLLGVTDG VMWIATFEGY FFQKLVSRGY
ISWGRSGWVV QNIWQMAYLG SVIGWAHFRQ WPWTHTIFVV LHGLVFLMKQ HSYAFYNGYL
SGVYRRKRLL EQKLKDLENL EPLLSPPTSP TSPRESFIEV SSSVDLSPKT DDMKRRRPST
GPRTSTNFKK EHSLVASVAA AIESGQSLTA DQMSTMSDIV KHEISDLEKE LRGKSDSNAK
AYPNNLTLGN YIEYTCFPTL VYELDYPRQE RTNWWYVLEK SVATFGVLCV MQVISQGFIY
PLVRRSLDMK ETNMPLEDRW REFPFIVSDM LFPMLIEQLL TWYVIWECIL NVLAEVTRFA
DRGFYGDWWN SVTWDQYARD WNRPVHNFLL RHVYHSSIST FHLSRKAATF VTFLLSALVH
EMCMALIFSK VRGYLFWMQL LQMPLVAFSR SKFMKGRTVL GNAIFWTGLF IGPALLTSLY
LWKSGVLRFV
//
