ID M2ZZE4_PSEFD Unreviewed; 2686 AA.
AC M2ZZE4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE Flags: Fragment;
GN ORFNames=MYCFIDRAFT_93888 {ECO:0000313|EMBL:EME77536.1};
OS Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS fungus) (Mycosphaerella fijiensis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=383855 {ECO:0000313|EMBL:EME77536.1, ECO:0000313|Proteomes:UP000016932};
RN [1] {ECO:0000313|EMBL:EME77536.1, ECO:0000313|Proteomes:UP000016932}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIRAD86 {ECO:0000313|EMBL:EME77536.1,
RC ECO:0000313|Proteomes:UP000016932};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
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DR EMBL; KB446564; EME77536.1; -; Genomic_DNA.
DR RefSeq; XP_007931362.1; XM_007933171.1.
DR STRING; 383855.M2ZZE4; -.
DR GeneID; 19342872; -.
DR KEGG; pfj:MYCFIDRAFT_93888; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_60_1_1; -.
DR OrthoDB; 2190653at2759; -.
DR Proteomes; UP000016932; Unassembled WGS sequence.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0043604; P:amide biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd05918; A_NRPS_SidN3_like; 1.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd19542; CT_NRPS-like; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 3.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR PANTHER; PTHR45527:SF16; NONRIBOSOMAL PEPTIDE SYNTHETASE ASQK; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000016932}.
FT DOMAIN 649..725
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2160..2235
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EME77536.1"
FT NON_TER 2686
FT /evidence="ECO:0000313|EMBL:EME77536.1"
SQ SEQUENCE 2686 AA; 298113 MW; 12BDA450F01B0683 CRC64;
LQAQYDPLVM DDKQMQRFLN QLANVISQLQ SGAFHDKRVR DIVLATEDDI QQVWAWNSTE
PHVETKKMCI HHLVTAQARK GPDRMAVSAW DGKLTYGQLD RLSSRLARHL RSLGILTKEQ
IVPACFEKSK WTLIAQLAVL KAEAAYTLID ATSPRERVDQ ICRQTNATLV LVSRGQLSHL
VDKVACCVVV DDASMAGLCS REGGDVDDEP GDPGSLAYVL FTSGSTGTPK GSLIEHASFT
SSCLAFAPSM RISESTRALQ FASYAFGASL FETLAVLLHG GCVCVPSEEQ RIAALPDFIA
REHVNWAFFT PSFLTTLRPQ DVLHHQPFTL LAGGEPISSE MQQLWTPLCD LINVYGQSET
SSACGVACIT SDTPNPRNIG RGVGARLWVT EVDNVDALAA VGAVGELIVH GPGVGRGYLG
QADDVVGPFL QEAPKWWCPD ASNGACSDDP SGHGNGELQQ RFFRTGDLVR YQPNGSLVHL
GRIDGQIKIN GQRIEVGEVE YHVKKQLLTL QQTGKSLTGT SETLGNLAVS VVAVPSSHAQ
SRNVLVAFIR VDTGMVKSGR RDYAAEVLGI SFNDQMNELL TAHLSWASRP QHYIRMSHFP
VTVTGKTDKK RLKSLATQLL QPASIASIPK GVVNGVSSSA QLPLTGTKSD PDHLEAMMCN
MWAQVLRIDP TQVNPGDNFL HLGGDSIDAI RLVNIASRSG ISTSMTDVLG HPVLKDLVRA
IPSPSPHGPL QNGTQNRSID CAPSAAQERL FFLDKMRPDQ TPWYYNIPLA VRLRGPLDIY
ALEMCLATLE RVHEPLRTTF HQTDVAGAIV QRIETPRCLI FKRPLHPIMS FDKARSVLEA
EQRRPFLLHA EHLWRANVYP CEDGTHILSI VLHHIIADGW SVDVLCRDLS NYYADVVQGA
DILSHVNPLP IQYRQHAAQQ QRELASGALQ SQIDYWKTEL ADSQAAELPT DHVRQQILSG
AAGIVKFELR GERYTRLQEF CKDHNATPFA VLLATFRATH YRATGAQDGI VGIPYSGRNT
PELQSLIGFF VNTQCVRLRI REDEESFISL VHQTKTAVLN ALKNQDVPFE RVVSELVPGV
RESSRNPLVQ LMFALHGQSE LGQIQLHGVE SEVIADAGPG LAAWSRFDLE FHLYRGEDAL
DGAVLFARDL FEQVTIENFL KTFMTLLDRG LEQPDTHLAV LSTTTTPKNY LADFLDDSIA
ASYPSHASVV DIFKAQCMRT PDATAVTDSA TGPLTYAQLD SRSDLVAMWL SDRHLAPEMV
VAIFAPRSCE TVVSILGILK AGLVYLPLDT RTPAGRVERI IDSVGASCRL LLVGSNQDPP
DIHIHHPGWD IVRMSQVFEQ RHLLESPLDC SRLHSPSPRS LAYIMFTSGS TGRPKGVMIE
HRGIVRLLCQ SHVTAQHPPA AKVAHISSLG FDATTWEIFS ALLNGGTVCC IDHEQVIDAL
ALGSQFQQEA IQVAMLTPAL LKQCLEYCPT MLSQLAVLNV AGARFDPRDA QKTRSLMSGE
LYNVYGPTEN TVLTTTYRLH PGDEYPNGVP VGTAINATGV FVMDSQQQLV APGIVGELVI
VGHGLARGYT DPALDHGRFI VLDDGVRQAR AYRTGDLVRR RATDDMIEFI GRADAQIKIR
GQRLELAEIE HTILEYNSGI KDAAVLACED NNEELTLVAF VTPSRTDTAT TSHVDSSHVR
DWSSHFELNT YQDISSIDPA KLGRDFVGWK SMIDGEIIPE SAMEEWLQDI MRVAVPEGEN
PGSVLEIGSG TGMILFNLNP EMESYIGLDP SQSAVNFTMS AIKSRPELVG KVEVRRGTAL
DIPSLGCIHP NLVIMNSVVQ YFPSIEYLNV VLKHILALPG VRKIVFGDIR SYALYNEFLS
AKTLHELRHS ASKEDFRRRM ESLREEEEEL LISPLYFTQL AEEFPDQIEH VEILPKIMRA
ETELNGYRFN AVIHVRGEQG TRPIALETPH DEWQDFVASG MDADILSDML QTRHYAPHIL
IGNIPYSNIM LEREIAAEID QENANSEGRE SWLSRAKEKA SAQPSMSTVD LVEVGKLHGW
DTKLSWARHG SQHGGLDVIF YHSQHAQSEP TPQFRFPTDT FTTTTPLCTQ PLQRKRRKAL
VSDISNNLRR QLPTYMIPAR IEILDQMPLN ASGKIDSSEL KRKATLLSKE HAPLRKVDLR
PKTEMETVIC EEIGIMLGLE NVSADDNFFD LGGHSLMATR FAVRLSSRLK ILVSVRDVFT
SPVVGQLAQV LESRVDHVDG PETSVSSVYA PFQLLGLQDG KSVLEQVEIE SQLDAPLRGH
VYDAYPATQT QQVFLQDGPR RNAAYVDLVG SIDCELLKHC CMAMVQRFDI LRTVFIQTRN
RFYQVVLDQV WVPIEIHEVH GSMDDVTGSI RDQHSQDPRL SLGSSWLRID ILVDQRHSTV
RLMVHMPHSM YDGASLQHWF RCLFIAYQGL DLPPSPPFAW YVKHMQDSRR EGYKFWREVL
HSSSPLTMTN LEFKGPADAG YRALRTIAIP SRNRSSTHTT ATVFTAAWAK VLGRESGRDD
INFGRLVSGR EALPEAHQSI VGPCVNVVPV RIRFSDIESS ASLLQEVQKQ YLDCIPFSTI
GLGEIRDHCT QWPRDDGAVD DARVLWSFVL FQESPAPMEF QQREVLLRTL PYSGPPTYEV
DVVGNVDPDG SHLHVLIYAR QRSASIATVD RMLHQLCEEV KELSES
//
