ID   M3AVV0_SPHMS            Unreviewed;      1194 AA.
AC   M3AVV0;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=R3H domain-containing protein {ECO:0000259|PROSITE:PS51061};
GN   ORFNames=SEPMUDRAFT_151207 {ECO:0000313|EMBL:EMF10211.1};
OS   Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS   musiva).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX   NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF10211.1, ECO:0000313|Proteomes:UP000016931};
RN   [1] {ECO:0000313|EMBL:EMF10211.1, ECO:0000313|Proteomes:UP000016931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SO2202 {ECO:0000313|EMBL:EMF10211.1,
RC   ECO:0000313|Proteomes:UP000016931};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NFX1 family.
CC       {ECO:0000256|ARBA:ARBA00007269}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KB456268; EMF10211.1; -; Genomic_DNA.
DR   RefSeq; XP_016758332.1; XM_016906672.1.
DR   AlphaFoldDB; M3AVV0; -.
DR   STRING; 692275.M3AVV0; -.
DR   GeneID; 27903809; -.
DR   eggNOG; KOG1952; Eukaryota.
DR   HOGENOM; CLU_005714_2_0_1; -.
DR   OMA; PRTSCED; -.
DR   OrthoDB; 1412at2759; -.
DR   Proteomes; UP000016931; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06008; NF-X1-zinc-finger; 5.
DR   Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR   InterPro; IPR034078; NFX1_fam.
DR   InterPro; IPR001374; R3H_dom.
DR   InterPro; IPR036867; R3H_dom_sf.
DR   InterPro; IPR000967; Znf_NFX1.
DR   PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR   PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR   Pfam; PF01424; R3H; 1.
DR   Pfam; PF01422; zf-NF-X1; 6.
DR   SMART; SM00393; R3H; 1.
DR   SMART; SM00438; ZnF_NFX; 8.
DR   SUPFAM; SSF82708; R3H domain; 1.
DR   PROSITE; PS51061; R3H; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          846..909
FT                   /note="R3H"
FT                   /evidence="ECO:0000259|PROSITE:PS51061"
FT   REGION          1..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          131..166
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1132..1194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..98
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1194 AA;  130294 MW;  35219410DAEED1CA CRC64;
     MDTGAPADSE VTHRRRQPRR ARGSRRGGGD DAALAFRPAS IAPAAPVHDR QTIPDGVGQR
     GGRGGGGGGG RGRGRSGRGG GGQAPQNRTT VNGRTFGGAL TRADTTTSQT STGNLQAAAP
     VFVPGQLHVQ NVPLKQPIER DPRSHRQTKQ RRMSKSQAPD IATRTHEDID NRHYECAICT
     SEVLRNSKVW SCHTCWTVFH LKCIKQWSSN AGAAAAQSNT NGEPQMRQWR CPGCNLPKDD
     LPHSYSCWCE KETEPRPLQG IPPHSCGQTC GKERPRKCPH PCQLTCHAGP CPPCTHMGPT
     KTCYCGSHES TKRCMETNYE SGWSCGEVCG SVMACGEHTC PQACHDGPCG PCEIRLPARC
     YCGQMEKDVL CSDRGLPVES NRKHSLSDLA VTESATDLQG SETVLETWTG VFNCGSTCGR
     TLDCNHHQCV KKCHPQDADS GHCPRSPDVV THCSCGKTPL HELSDAPRTS CEDDIPSCSK
     PCDKSLPCGH PCPQVCHVGD CGSCLRTVTI SCRCGRSSHT TMCHQGRDEP PQCMRICRST
     LNCGRHMCDE HCCAGEQKAR ERQASRKKGR PFGSAPRAAA EGYEAEHICT RQCGRPLKCG
     NHSCEELCHK GPCGSCREAI FDEITCHCER TVLQPPLPCG TQPPPCRYAC ERPKSCGHPQ
     VAHNCHSDED TCPKCPFLTP KMCMCGKKAL KNQQCWLRDV SCGNVCGQKL KCGVHFCRKQ
     CHRKGQCEDA GGKACAQPCG KEKKICGHPD EAPCHAPFGC KEIKPCNSKI FITCECQAQK
     QEIKCGASST TEGNNLKSLP CTEDCARLER NRKLAVALNI DQSTHVDGGD HIPFSTDTLD
     LFAAHPKWGQ VQEREFRVFA ASDDEKRLRF KPMSAQQRSF IHSLAEDFGL DSESLDPEPH
     RHVMIWKTPR FVSAPNKTLA DSLRLRQQAQ RSVYASTNAS DNEGAPVKSA SKTFEPFNSF
     RIIKPRFGLT IEEVRSEVET VLRTAYPFTF DIEFLPSEDV VLKAISRTLS AQDLERMLLN
     LKDPLGTKIA DRSYGSMQLC TTDSSLNITR FESDGMGSDG WSRVAAKKSA PRIALQSNTY
     GTTNAFSALS GGKVTFAKKA PLAKVVKRRP APVVDDWEAA EVEEEEKERI AYASASEGEA
     LGVERSRDPL PLEGSSSDES VAAETAVAKV DETIDEGAET RDWAEGVTLA EQTG
//