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Database: UniProt
Entry: M3BU43_9ACTN
LinkDB: M3BU43_9ACTN
Original site: M3BU43_9ACTN 
ID   M3BU43_9ACTN            Unreviewed;       168 AA.
AC   M3BU43;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 60.
DE   SubName: Full=RNA polymerase ECF-subfamily sigma factor {ECO:0000313|EMBL:EMF27464.1};
GN   ORFNames=H114_19355 {ECO:0000313|EMBL:EMF27464.1};
OS   Streptomyces gancidicus BKS 13-15.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces; Streptomyces pseudogriseolus group.
OX   NCBI_TaxID=1284664 {ECO:0000313|EMBL:EMF27464.1, ECO:0000313|Proteomes:UP000011732};
RN   [1] {ECO:0000313|EMBL:EMF27464.1, ECO:0000313|Proteomes:UP000011732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BKS 13-15 {ECO:0000313|EMBL:EMF27464.1,
RC   ECO:0000313|Proteomes:UP000011732};
RX   PubMed=23599292;
RA   Kumar S., Kaur N., Singh N.K., Raghava G.P., Mayilraj S.;
RT   "Draft Genome Sequence of Streptomyces gancidicus Strain BKS 13-15.";
RL   Genome Announc. 1:E00150-13(2013).
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMF27464.1}.
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DR   EMBL; AOHP01000077; EMF27464.1; -; Genomic_DNA.
DR   RefSeq; WP_006133809.1; NZ_AOHP01000077.1.
DR   AlphaFoldDB; M3BU43; -.
DR   PATRIC; fig|1284664.3.peg.3893; -.
DR   OrthoDB; 3678480at2; -.
DR   Proteomes; UP000011732; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR014325; RNA_pol_sigma-E_actinobac.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02983; SigE-fam_strep; 1.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF66; ECF RNA POLYMERASE SIGMA FACTOR SIGM; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011732};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          20..79
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          105..156
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
SQ   SEQUENCE   168 AA;  18691 MW;  96C184D801030E77 CRC64;
     MQRFRADGFD EFVAARWSAL LHVARLLTGG DRQRAEDLVQ ESLVKLWFAW PKVAEQAPEA
     YVRQVLVRLA ARSARRRWWG ERPVGELPDR AGPGDVSAAV AERSRLEAAL ALLTPRQRAA
     VVLRYYEDLP EGQVAQALGC PVGTARSHAS RGVARLREIL SDSARPVK
//
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