ID   M3CCR5_SPHMS            Unreviewed;       435 AA.
AC   M3CCR5;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=Pre-mRNA-splicing factor {ECO:0000256|RuleBase:RU369096};
GN   ORFNames=SEPMUDRAFT_151202 {ECO:0000313|EMBL:EMF10202.1};
OS   Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS   musiva).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX   NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF10202.1, ECO:0000313|Proteomes:UP000016931};
RN   [1] {ECO:0000313|EMBL:EMF10202.1, ECO:0000313|Proteomes:UP000016931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SO2202 {ECO:0000313|EMBL:EMF10202.1,
RC   ECO:0000313|Proteomes:UP000016931};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA   Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA   LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA   Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA   Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA   Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT   genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
CC   -!- FUNCTION: Involved in spliceosome maturation and the first step of pre-
CC       mRNA splicing. {ECO:0000256|RuleBase:RU369096}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU369096}.
CC   -!- SIMILARITY: Belongs to the SPP2 family. {ECO:0000256|ARBA:ARBA00008576,
CC       ECO:0000256|RuleBase:RU369096}.
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DR   EMBL; KB456268; EMF10202.1; -; Genomic_DNA.
DR   RefSeq; XP_016758323.1; XM_016906669.1.
DR   AlphaFoldDB; M3CCR5; -.
DR   STRING; 692275.M3CCR5; -.
DR   GeneID; 27903806; -.
DR   eggNOG; ENOG502RZY8; Eukaryota.
DR   HOGENOM; CLU_033338_1_0_1; -.
DR   OMA; AWGKSAM; -.
DR   OrthoDB; 55448at2759; -.
DR   Proteomes; UP000016931; Unassembled WGS sequence.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:UniProtKB-UniRule.
DR   InterPro; IPR000467; G_patch_dom.
DR   InterPro; IPR045166; Spp2-like.
DR   InterPro; IPR026822; Spp2/MOS2_G-patch.
DR   PANTHER; PTHR15818; G PATCH AND KOW-CONTAINING; 1.
DR   PANTHER; PTHR15818:SF2; G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN; 1.
DR   Pfam; PF12656; G-patch_2; 1.
DR   PROSITE; PS50174; G_PATCH; 1.
PE   3: Inferred from homology;
KW   mRNA processing {ECO:0000256|RuleBase:RU369096};
KW   mRNA splicing {ECO:0000256|RuleBase:RU369096};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369096};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW   Spliceosome {ECO:0000256|RuleBase:RU369096}.
FT   DOMAIN          222..271
FT                   /note="G-patch"
FT                   /evidence="ECO:0000259|PROSITE:PS50174"
FT   REGION          1..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          122..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          279..435
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        25..41
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..151
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        293..435
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   435 AA;  49816 MW;  FB82AE2142189273 CRC64;
     MSGNKISLSL GGARKLPQLT HGVKRPRTAL HDEDDDGATM DKAQAVSHFD STAGGAVNAS
     KEEEKNAPLL IAPQANRDWR DKASQRKRQK SGLPGNQDGS RADLDARMRD VEAKVEASKP
     KFGLNTYNNK RGNAEDEVMS GTGNISTNDD SISRNTEEKM EAAKSKTDDE LAMDALLGKT
     TTDKTLIIEG NNAPMTEGDA FEHDVASAPD MATLDDYARV PVEQFGAALL RGMGWKDGEG
     IGSQKGKRLA KDTGKLPERR AALLGIGAKE NAAMAQELGA WGKASRGKDA KIYNPVLIRD
     KKTGKTYTEE ELEKKKQDEE RRKYEMEFEK RERDRKPRDG EHHASRDRRR DHSRERTHGK
     EDRREREKSR RKDDPDSEAE YRRRKEREQH RRRERDEDYD RDSRRHRDHD SSGRERHHER
     DRRERDRERE RERRR
//