ID M3D782_SPHMS Unreviewed; 497 AA.
AC M3D782;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:EMF14020.1};
GN ORFNames=SEPMUDRAFT_147876 {ECO:0000313|EMBL:EMF14020.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF14020.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF14020.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF14020.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
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DR EMBL; KB456262; EMF14020.1; -; Genomic_DNA.
DR RefSeq; XP_016762141.1; XM_016904572.1.
DR AlphaFoldDB; M3D782; -.
DR STRING; 692275.M3D782; -.
DR GeneID; 27901709; -.
DR eggNOG; KOG4505; Eukaryota.
DR HOGENOM; CLU_008635_5_0_1; -.
DR OMA; TFGWLIC; -.
DR OrthoDB; 1607026at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR GO; GO:0120029; P:proton export across plasma membrane; IEA:InterPro.
DR GO; GO:0042391; P:regulation of membrane potential; IEA:InterPro.
DR GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR004712; Na+/H+_antiporter_fungi.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR31382; NA(+)/H(+) ANTIPORTER; 1.
DR PANTHER; PTHR31382:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..446
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
FT REGION 474..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 54821 MW; 79370E7CC1DCC971 CRC64;
MVWDQIEATP PHITYLLLST FLISYVLFTN FLRNRLHLSE PPIALIVGIL LGPAVLQWLT
PNFCDSEGCG SEFAGGWGWG DGTVQEITRV IVGIQVFAVG VELPKYYASR HWRSVAMLLG
PVMAFGWGIC AIFAKYIFQI DWSTALVISA CLTPTDPVLA ASILSNSQFS TRVPKRLKDM
LSAESGCNDG VSFPFLYMGL FFLTQHSTGD AVRDWFLITI LWQCTFGIFI GLVIGVTFNW
VLRFSDARNY IDKAGFTVFY LLLAIFCVGV GSTLDSDDFL VAFGAGYGFA RDGWFAKKTK
EAHLPHIIDL LLNSSMFVYV GTILPFQSYH DKILTPWITV PRLLGFLVLV LLFRRIPVVL
ATYRFIPDIR TIREALFCGH FGPMGLGALF LAVEGRAVLE TGTSTPDSHP PEYSPPLTDR
QKAIETIWPV VSFIVLGSTL VHGLSVLVLS VASHLRKYKK DRAGVVAAET DPLTGMVHDE
GDGGSASETT DDEHGQV
//
