ID M3DE63_SPHMS Unreviewed; 536 AA.
AC M3DE63;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 3 {ECO:0000313|EMBL:EMF16060.1};
GN ORFNames=SEPMUDRAFT_81456 {ECO:0000313|EMBL:EMF16060.1};
OS Sphaerulina musiva (strain SO2202) (Poplar stem canker fungus) (Septoria
OS musiva).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Sphaerulina.
OX NCBI_TaxID=692275 {ECO:0000313|EMBL:EMF16060.1, ECO:0000313|Proteomes:UP000016931};
RN [1] {ECO:0000313|EMBL:EMF16060.1, ECO:0000313|Proteomes:UP000016931}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SO2202 {ECO:0000313|EMBL:EMF16060.1,
RC ECO:0000313|Proteomes:UP000016931};
RX PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A., Barry K.W.,
RA Condon B.J., Copeland A.C., Dhillon B., Glaser F., Hesse C.N., Kosti I.,
RA LaButti K., Lindquist E.A., Lucas S., Salamov A.A., Bradshaw R.E.,
RA Ciuffetti L., Hamelin R.C., Kema G.H.J., Lawrence C., Scott J.A.,
RA Spatafora J.W., Turgeon B.G., de Wit P.J.G.M., Zhong S., Goodwin S.B.,
RA Grigoriev I.V.;
RT "Diverse lifestyles and strategies of plant pathogenesis encoded in the
RT genomes of eighteen Dothideomycetes fungi.";
RL PLoS Pathog. 8:E1003037-E1003037(2012).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB456261; EMF16060.1; -; Genomic_DNA.
DR RefSeq; XP_016764181.1; XM_016910274.1.
DR AlphaFoldDB; M3DE63; -.
DR STRING; 692275.M3DE63; -.
DR GeneID; 27907411; -.
DR eggNOG; KOG0234; Eukaryota.
DR HOGENOM; CLU_006383_0_2_1; -.
DR OMA; VKTHVFH; -.
DR OrthoDB; 1381184at2759; -.
DR Proteomes; UP000016931; Unassembled WGS sequence.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR PANTHER; PTHR10606:SF39; 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:EMF16060.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000016931};
KW Transferase {ECO:0000313|EMBL:EMF16060.1}.
FT DOMAIN 45..264
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
FT REGION 492..536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..536
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 60398 MW; 7FFD0FD2FED2F8F1 CRC64;
MDTLLTADVA GSAPNFRRRS STYVDAIHDL PEKASMAPAQ LYSTESGRLF HSGRIVIATV
GLPARGKTHI SVALARYLRW LGVKTHIFHL GDYRRAFVGA KGEVPEDYFH INASTSSVLL
RNKILKKCRE DIFHFLNHEN GQIAIYDAVN PLATGRRALA REFEKQGVQT MFIECTCSDE
RIIEENVRAV KISSPDYVGW KPEDAVQDYL RRINARIPHY EGVEERDLHY VKMINAGERV
IVNSCAFGYL SQRIVFYLLN LHIKSRQMYF VRAGTTREEE TFKGDASLSA EGQDYARKMT
DAIVAHREME RETLIKNGAP ESTASKPLQI WTSTRKRTVE TASYLEQKGY RVRQRSQMSQ
LNPGVCEKLS ERRIRELFPE EVAKHEQDPY HHRYPRAESY HDLAVRLEPI ILELEREQND
LLIIAHESVL RVLYGYLMAC SAHDIPTLEF PRDEIIEVIP ASYNNSARRI HISDLPSSII
PGSPQDIQIP VPQSGVASPM GLSTPAGAAT PVSSFGPEVS VTQPAGESAN SLSPRV
//
