ID   M3FC29_LEPBO            Unreviewed;       449 AA.
AC   M3FC29;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Transporter, CPA2 family {ECO:0000313|EMBL:EMF99432.1};
GN   ORFNames=LEP1GSC123_4600 {ECO:0000313|EMBL:EMF99432.1};
OS   Leptospira borgpetersenii str. 200701203.
OC   Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae;
OC   Leptospira.
OX   NCBI_TaxID=1193007 {ECO:0000313|EMBL:EMF99432.1, ECO:0000313|Proteomes:UP000011783};
RN   [1] {ECO:0000313|EMBL:EMF99432.1, ECO:0000313|Proteomes:UP000011783}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=200701203 {ECO:0000313|EMBL:EMF99432.1,
RC   ECO:0000313|Proteomes:UP000011783};
RA   Harkins D.M., Durkin A.S., Brinkac L.M., Haft D.H., Selengut J.D.,
RA   Sanka R., DePew J., Purushe J., Picardeau M., Werts C., Goarant C.,
RA   Vinetz J.M., Sutton G.G., Nierman W.C., Fouts D.E.;
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EMF99432.1}.
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DR   EMBL; AKWO02000073; EMF99432.1; -; Genomic_DNA.
DR   AlphaFoldDB; M3FC29; -.
DR   BioCyc; LBOR1193007:G11KN-28-MONOMER; -.
DR   Proteomes; UP000011783; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR   Gene3D; 6.10.140.1330; -; 1.
DR   Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR   PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR   PROSITE; PS51202; RCK_C; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011783};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        46..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        78..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..252
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        258..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          363..444
FT                   /note="RCK C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51202"
SQ   SEQUENCE   449 AA;  48899 MW;  BD74928F506D96AC CRC64;
     MAAGSDGLGG IEFDNPVLAK QVGSIALAYI LFSGGLETEW LKIKPVLWKG IVLGNLGVLI
     TGAVMGLFSV YVLGFSPIIG FLLGAVVSST DAAAVFNVLR TRNTGMKKGL TSLLELESGS
     NDPLAVLLTV SILSLLGPHP PQIEELALHI FMQFSIGTVA GVIFGYAIYK GLNRIKLEYE
     GLYPVLISAS VLFVYSATEL IQGNPFLSVY IAGLVLGNQS FVHKRSNLRF LDGIAWLMQI
     IMFLTLGLLV YPSRIPPLFG TGIVFSLFLV FIARPIAVFV SLFRSGYNIR EKLLVSWIGL
     RGAAPIILAT FPFAQGLAGS DKIFHLVFFT VLVSLLLQGT SVPQVVRWLG LDAPLEQRAS
     YPFEFENREQ SDSNLLEFIV PYGSNSAGKF VYSLNFPENS LITLIYRGDR HIVPTGKTTL
     EEGDVLLILT PKGSEDKIRD ILSQMETTI
//