ID M3JXD5_CANMX Unreviewed; 3008 AA.
AC M3JXD5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Vacuolar protein sorting-associated protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=G210_2649 {ECO:0000313|EMBL:EMG47074.1};
OS Candida maltosa (strain Xu316) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=1245528 {ECO:0000313|EMBL:EMG47074.1, ECO:0000313|Proteomes:UP000011777};
RN [1] {ECO:0000313|EMBL:EMG47074.1, ECO:0000313|Proteomes:UP000011777}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Xu316 {ECO:0000313|Proteomes:UP000011777};
RA Yu J., Wang Q., Geng X., Bao W., He P., Cai J.;
RT "Genome sequence of Candida maltosa Xu316, a potential industrial strain
RT for xylitol and ethanol production.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS13 family.
CC {ECO:0000256|ARBA:ARBA00006545}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EMG47074.1}.
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DR EMBL; AOGT01001733; EMG47074.1; -; Genomic_DNA.
DR STRING; 1245528.M3JXD5; -.
DR eggNOG; KOG1809; Eukaryota.
DR HOGENOM; CLU_000135_0_0_1; -.
DR OMA; SGWRPIR; -.
DR OrthoDB; 199953at2759; -.
DR Proteomes; UP000011777; Unassembled WGS sequence.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR InterPro; IPR026847; VPS13.
DR InterPro; IPR026854; VPS13-like_N.
DR InterPro; IPR049424; VPS13_C.
DR InterPro; IPR031645; VPS13_DH-like.
DR InterPro; IPR031646; VPS13_extend_chorein.
DR InterPro; IPR017148; VPS13_fungi.
DR InterPro; IPR031642; VPS13_mid_RBG.
DR InterPro; IPR009543; VPS13_VAB.
DR PANTHER; PTHR16166:SF93; INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13; 1.
DR PANTHER; PTHR16166; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13; 1.
DR Pfam; PF12624; Chorein_N; 1.
DR Pfam; PF21679; VPS13_C; 1.
DR Pfam; PF16909; VPS13_DH-like; 1.
DR Pfam; PF16908; VPS13_ext_chorein; 1.
DR Pfam; PF16910; VPS13_mid_rpt; 1.
DR Pfam; PF06650; VPS13_VAB; 1.
DR PIRSF; PIRSF037235; VPS13_fungi; 1.
PE 3: Inferred from homology;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Reference proteome {ECO:0000313|Proteomes:UP000011777};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..115
FT /note="Chorein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12624"
FT DOMAIN 137..360
FT /note="Vacuolar protein sorting-associated protein 13
FT extended chorein"
FT /evidence="ECO:0000259|Pfam:PF16908"
FT DOMAIN 578..812
FT /note="VPS13 middle RBG modules"
FT /evidence="ECO:0000259|Pfam:PF16910"
FT DOMAIN 1873..2443
FT /note="Vacuolar protein sorting-associated protein 13 VPS13
FT adaptor binding"
FT /evidence="ECO:0000259|Pfam:PF06650"
FT DOMAIN 2696..2872
FT /note="Vacuolar protein sorting-associated protein 13 DH-
FT like"
FT /evidence="ECO:0000259|Pfam:PF16909"
FT DOMAIN 2969..2993
FT /note="Intermembrane lipid transfer protein VPS13 C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF21679"
FT REGION 436..457
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1328..1349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1491..1524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 442..457
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3008 AA; 339471 MW; D70627E3D61EBE71 CRC64;
MFESLVANLL NRVLGSYLEN FDTNQLNIGI WSGDVKLRNL RLKKESLDKF KLPVDVKFGH
LGELTLQIPW SNLKGKPVRI IIQDVYLLAS PIVMQDFDLE EEEKRSQAVK QEKLSQLEAF
LEAKSQELGE DLENESFVES LVTKIIDNLQ VTIKNIHIRY EDDSILTESP YSIGFSLDEL
SAVSTDEDWV PSFINITQSL TRKLVTLSNL SCYMDTQNSK LYSHLNREEI LSAFQSTMSD
IEYLLKPVTG NGKLTVNKLG TTEKTPHIES DLFFEEFGVE LNSQQYQDLL WTASKFHWIM
KTEKFRKFRP KLPPSEAPKE WFKYAAESVL NEIHERNYKW SWAYFEKRRD QRKAYIKLWK
LKLQGKITPE EQKELDDLEW DLPFEDIKLY RSFTRNELKK DKQHYSLYHS ETKPAQTTNT
SGGWFSGWWG AGNNTTTTTN KEDDASSHEE CDDTDEKKLD LSLTDEQRKA LYDAIDYDGS
TATEVDIPAE WVKMKITARL DKGGLTIKRD KTTNLAEVVF EGCKTDFLER PNSFLAKFQM
DEFRVEDGSG TSIYKHVVSV KQNSDIQTSH ESFLQLAFEN NPLDQSADSN LFAKLKSMTI
YYNPKFIEEI VKFFTPPKIH LDTVGAIMNA AESTVEGLTA QTRIGLEYAL EEHKTINVRL
DLQAPLVILP LDPSSVKSPV AILDAGHISV MSDLVDKSKV KEYKEKDQYS KEDWKSLRTL
MYDKFHVNLQ DARFLVGHNI KTTMEQLYSD GKDRSAYMLD TFNLGLLLEV SILPDAQNLA
QIRVGGNVPK IALSINDFQY KTLMQIIDAA IPNTDFDTSD DSSIFKAFGN HRGAGDIDMD
EGNKQALTEK KKPVNNEQHQ FEFNFSVDLV QISLSRCIDG VTLQSEPLAD IIGESFNLNF
YKTLTDMFLT LKVFDISLLD HIEKSGVPEF QKLISSNSDN ETKNLLELNY NRKQRIVMFN
KKEIEVFDQD VDMQIAVVKF VVTRKSYLSL LNFVLNTFTD PNAAPTPADE LKHNAEDDEE
AAPQKINVKV GLESIIMVLN EDGIKLATLQ LSSAEIKVLL LPESMDVQGK LGAFTLHDEV
NVGCPRDSPM RNLIKIDGDN LATFSYKTFD VVTESKPTVV QFETGAMTIN FIESSFNRIL
SYLSQFLRMK AIYDSAREAA INQAAQLPAK LLFNLLIHAP TIVFPFEGSD NKRLVANLGE
IYAHNEYKDV INAIEFGIRK VSLLSHIQFE EEDVVQDSHM VDELDIGFNI DYCEDYVKGT
PTFTIDGKMP ELDMHLTEIQ LRMLTQLSES ISQAFTFDDV DSNMEDVEED AAYANEVLKH
NTKMIQGDAP TGEQIATSKN EETSQSTEIP PDHQMVDLKF NVPRVALTIY NRTEGVCHLE
TCPLSLFAMT GLVCKFDMTQ DTHFKSNVKV KSFVVEDVRK NTDSKFPVII PAADDVDNQF
DVSISTSGPA ENKNTTVMLT VEKPKTILAL DYLFELQFFV NKATEPDSQI ETIGSIPRQK
SRTSVVSNSA NAPSSPANAE NTNVHEPSKL GFSINIIEPS VILLADDSKE NTEAVVFRVG
QILITQQNVI SLAANNIGMY LMLMNEAENS RYRIIDDFSI SFAHDSRGST ATDFLTNIQA
SIDPLIIRVS LRDIRLALAI FNRANQLYIK HQGLTQSADD SNDEYKFSKD FKKKLTQYAP
SIVSAFSEEM EPVPRPEIPE GVVIVKGEEL TASFGGLRFV LIGEVSELPI LDLNVKPFEA
HAINWSTDLS AEVHIEQFIN IFNYARSAWE PLVEPWPIAV YASKTRHPKE QLLVEVISRQ
SAQITLTSKA IALLSQVSNL ITSDEKLKPR GEDYPYIIVN ETGYDVEVWS DVQNSNKKAE
IKSWESIPWS FEDWRKIREN LDADDASSLG IKFLNTDYQD IDKITASSVG EELYVMYPPV
DGIHNRLSVD IVLREDNVKV IKLRSTVVIE NDADIPIVVG LGDDKELVIE SKQAKSIPID
VVYSGRLRIK PNIHTPYGWS EEQLYWKDAL KNSSSLKCPA ENPGDKSIYY FQAEAVFDKD
EALAKVYPHM SIVVSAPLEI ENLLPFDFTY RLYDKKAKKD WTGSVRKGVK SYVHVVSLDN
LLLLSVQPVN CTLQRSEFAI INHPKKSEFE REHTLTLQDA NGRFLKLRIY YPRKQSDSTS
LKVVVYSPYV ILNRTNLNLI VNHHNNQVES YGGGSSNNSS DSERKITPIM FSFDKHGDTK
NRATIKAEDT VWSQPMSFDA LGQSNELKLQ VLGKQREIDI GVSITEGEGK YNLTKVVSIA
PRYIFMNKLE EELQLVEVGT TNPLNIKPGT SLPLYGLRCL EKKSIMVKFL SGSGPMSWSQ
PFCINDVGQL FIKVLKKDIG QVLVKCTIML EDATIFIHVE NGNDQWPYSI RNFTDEEFYI
YQNDPNINAN GEIVKSETPY KPIYYKIPPK SVMPYAYDYP NAIIKEIIVR SHGRERAVSL
AEIGNLKPFR LPHTQDREQA IVDLNVVADG PTQSLIITNY DPSTSLYKLK GDAITSSTSV
ANGGTQFEAV ENDENYHTKI VTKFDGLGLS LINTNDQELC YITLKGLEFR YNESDLYQTV
SAKLKWIQID NQLYGGIFPL ILYPTVIPKT GKELNSHPAL SGSICKVKDD SHGVLFIKYA
TLLLQEMTIE IDEDFLFALL DFSKFPGASW NKEQVDRLCD DNLNIPEPVK LSDTSDVYFE
ALHLQPIQTN LSFVRTERVN AEDKIASQST VMFFVNVLTM AIGNINDAPI KLNALFIENI
RVPTPILVDS IQTHYRQAFF YQLHNIIGSA DFLGNPVGLF NLLSSGVIDI FYEPYQGFVL
NDRPQELGIG LAKGGLSFVK KSVFGFSDSF AKVTGSIAKG LSVATMDKEF QERRRLNTRR
NRPKHALYGF ATGANSFFDS ISSGLTGVAT APIEGASTEG AAGFFKGLGK GIVGLPTKTA
IGFFDLASNV SEGIRNTTTV FDGEGLDKVR LPRYINPNGI IKPYSQREAQ GQYRRDGRIA
FVQINHIV
//
