ID M3TW94_9ACTN Unreviewed; 407 AA.
AC M3TW94;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative acetyl-CoA acyltransferase {ECO:0000313|EMBL:GAC85916.1};
GN ORFNames=GP2_045_00310 {ECO:0000313|EMBL:GAC85916.1};
OS Gordonia paraffinivorans NBRC 108238.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1223543 {ECO:0000313|EMBL:GAC85916.1, ECO:0000313|Proteomes:UP000035021};
RN [1] {ECO:0000313|EMBL:GAC85916.1, ECO:0000313|Proteomes:UP000035021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108238 {ECO:0000313|EMBL:GAC85916.1,
RC ECO:0000313|Proteomes:UP000035021};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia paraffinivorans NBRC 108238.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC85916.1}.
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DR EMBL; BAOQ01000045; GAC85916.1; -; Genomic_DNA.
DR RefSeq; WP_006902177.1; NZ_BAOQ01000045.1.
DR AlphaFoldDB; M3TW94; -.
DR STRING; 1223543.GP2_045_00310; -.
DR eggNOG; COG0183; Bacteria.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000035021; Unassembled WGS sequence.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF8; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:GAC85916.1};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:GAC85916.1}.
FT DOMAIN 5..275
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 283..405
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 90
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 362
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 392
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 407 AA; 42595 MW; CCD0BCA5305ABEF8 CRC64;
MAEAVIVSTA RSPIGRAAKG SLKDVRPDEL SRQMVAAALT KVPELDPADI EDIHWGIGQP
GGQGAYNIAR VIAVELGYDH VPGVTVNRYC SSSLQTTRMA MHAIKAGEAD VIISGGVESV
SSFGISGGAD GAPNSKNPLF DDAQARTEQA AQGGAGVWHD PRQDGLLPDV YIAMGQTAEN
VATLTGISRE DQDRWGVLSQ NRAEEAIKSG FFEREIDPVT LPDGTKVTTD DGPRAGTTYE
KVSQLKPVFR PDGTITAGNA CPLNDGAAAL VVMSDTKAKE LGLTPLARVV ATAATGLSPE
IMGLGPIEAI RKVLRVAGMS LSDIDLFEIN EAFAVQVLGS ANELGIDHDK LNVSGGAIAL
GHPFGMTGAR ITTTLLNNLR THDKTFGIES MCVGGGQGMA MILERLN
//
