ID   M3V4W7_9ACTN            Unreviewed;       358 AA.
AC   M3V4W7;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Putative zinc-containing alcohol dehydrogenase {ECO:0000313|EMBL:GAC84622.1};
GN   ORFNames=GP2_024_00490 {ECO:0000313|EMBL:GAC84622.1};
OS   Gordonia paraffinivorans NBRC 108238.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC   Gordonia.
OX   NCBI_TaxID=1223543 {ECO:0000313|EMBL:GAC84622.1, ECO:0000313|Proteomes:UP000035021};
RN   [1] {ECO:0000313|EMBL:GAC84622.1, ECO:0000313|Proteomes:UP000035021}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 108238 {ECO:0000313|EMBL:GAC84622.1,
RC   ECO:0000313|Proteomes:UP000035021};
RA   Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA   Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT   "Whole genome shotgun sequence of Gordonia paraffinivorans NBRC 108238.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAC84622.1}.
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DR   EMBL; BAOQ01000024; GAC84622.1; -; Genomic_DNA.
DR   RefSeq; WP_006900855.1; NZ_BAOQ01000024.1.
DR   AlphaFoldDB; M3V4W7; -.
DR   STRING; 1223543.GP2_024_00490; -.
DR   eggNOG; COG1062; Bacteria.
DR   OrthoDB; 334894at2; -.
DR   Proteomes; UP000035021; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08279; Zn_ADH_class_III; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43350:SF19; RIBULOSE-5-PHOSPHATE REDUCTASE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          10..353
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   358 AA;  37312 MW;  F218C523FAE00820 CRC64;
     MRAAVIWEAG SPFEVRSDAT RDPAGPGQVA VRIRAAGVCQ TDMSLASGAF GQPMPVVLGH
     EGAGEVLEVG PDVTGVAVGD RVLVTWVPPC GHCYHCVRHE TYICANRKRS SEQGNSSGLA
     VGGTPVQVGL GTGTFAEETV VPVSGIIPLP ADIPFELAAL LGCAVPTGFG AAVNSAKVVP
     GDSVLVIGCG AVGLSSLQGA RIAGAAELVA VDPQPGRQDL ARRFGATHAY GPDDDPRQAL
     TDSPGFDVVI DAVAHSSTIT AAWRAARRGG RVVIVGAGRP EDVVELTAQE LFHDEKQLIG
     SYYGSSDMQR ELPRLVALWR TGRLNLDGMV DEVVDLEAIN EVAAGQREGR TLRTMLRL
//