ID M3VI38_9ACTN Unreviewed; 338 AA.
AC M3VI38;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Putative zinc-containing alcohol dehydrogenase {ECO:0000313|EMBL:GAC83049.1};
GN ORFNames=GP2_008_00490 {ECO:0000313|EMBL:GAC83049.1};
OS Gordonia paraffinivorans NBRC 108238.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1223543 {ECO:0000313|EMBL:GAC83049.1, ECO:0000313|Proteomes:UP000035021};
RN [1] {ECO:0000313|EMBL:GAC83049.1, ECO:0000313|Proteomes:UP000035021}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108238 {ECO:0000313|EMBL:GAC83049.1,
RC ECO:0000313|Proteomes:UP000035021};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Ando Y., Baba S., Ohji S.,
RA Hamada M., Tamura T., Yamazoe A., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia paraffinivorans NBRC 108238.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC83049.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAOQ01000008; GAC83049.1; -; Genomic_DNA.
DR RefSeq; WP_006899287.1; NZ_BAOQ01000008.1.
DR AlphaFoldDB; M3VI38; -.
DR STRING; 1223543.GP2_008_00490; -.
DR eggNOG; COG1063; Bacteria.
DR OrthoDB; 9797931at2; -.
DR Proteomes; UP000035021; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43189:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01; 1.
DR PANTHER; PTHR43189; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C1198.01-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 27..132
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 175..296
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 338 AA; 33969 MW; FDD7599E6F4B98FE CRC64;
MRAAVTTGRA GADAFEVTEL PDPTPGPGDL VLRVAANGIC GSDLSTAPFL PPGVVMGHEF
AGEVVAIGPR SGPGGDTDFR VGDLVASMPV RGCHRCRACL AGDIARCPSA QTLGLGVLPG
ALAEFVVVGA AESVRVEGVD PVEGALVEPL AVGLHAVTRA AIAPDDRVLV LGAGPVGTAA
LHWLSRGVAG EVICSDPSPG RRAAALDAGA SAVCVPEEVP GHVRDGFDVV IECVGKPGMV
ASALDAVATH GRIVVAGVCL SEDRFMPVAG VVKEVSIHFV SYYTRAEFAT AAAELSSGAV
GSSTLVSAIV GLDAVGRVFT ELSEPNDHRK VLVAPAVG
//
