ID M3VVR3_FELCA Unreviewed; 234 AA.
AC M3VVR3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=Synaptogyrin {ECO:0000256|PIRNR:PIRNR011282};
GN Name=SYNGR4 {ECO:0000313|Ensembl:ENSFCAP00000000902.3,
GN ECO:0000313|VGNC:VGNC:65885};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000000902.3, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000000902.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000000902.3,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000000902.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000000902.3,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000000902.3}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000000902.3};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|PIRNR:PIRNR011282}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|PIRNR:PIRNR011282}.
CC -!- SIMILARITY: Belongs to the synaptogyrin family.
CC {ECO:0000256|ARBA:ARBA00010252, ECO:0000256|PIRNR:PIRNR011282}.
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DR EMBL; AANG04000747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003997745.3; XM_003997696.4.
DR AlphaFoldDB; M3VVR3; -.
DR STRING; 9685.ENSFCAP00000000902; -.
DR PaxDb; 9685-ENSFCAP00000000902; -.
DR Ensembl; ENSFCAT00000000969.6; ENSFCAP00000000902.3; ENSFCAG00000000969.6.
DR GeneID; 101088705; -.
DR KEGG; fca:101088705; -.
DR CTD; 23546; -.
DR VGNC; VGNC:65885; SYNGR4.
DR eggNOG; KOG4016; Eukaryota.
DR GeneTree; ENSGT00950000182935; -.
DR HOGENOM; CLU_1209470_0_0_1; -.
DR InParanoid; M3VVR3; -.
DR OMA; IWIFQAY; -.
DR OrthoDB; 4177492at2759; -.
DR Proteomes; UP000011712; Chromosome E2.
DR Bgee; ENSFCAG00000000969; Expressed in testis and 8 other cell types or tissues.
DR GO; GO:0031594; C:neuromuscular junction; IBA:GO_Central.
DR GO; GO:0030672; C:synaptic vesicle membrane; IBA:GO_Central.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR016579; Synaptogyrin.
DR PANTHER; PTHR10838; SYNAPTOGYRIN; 1.
DR PANTHER; PTHR10838:SF22; SYNAPTOGYRIN-4; 1.
DR Pfam; PF01284; MARVEL; 1.
DR PIRSF; PIRSF011282; Synaptogyrin; 1.
DR PROSITE; PS51225; MARVEL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR011282, ECO:0000256|PROSITE-
KW ProRule:PRU00581}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|PIRNR:PIRNR011282, ECO:0000256|PROSITE-
KW ProRule:PRU00581}; Transmembrane helix {ECO:0000256|PIRNR:PIRNR011282}.
FT TRANSMEM 24..42
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 62..86
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 146..165
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT DOMAIN 18..169
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
SQ SEQUENCE 234 AA; 25220 MW; 5D8E45084D2976D3 CRC64;
MHIPESLQDL ADSEAVQFLK RPKTITRIFA GVFSLVVFSS LLTDGHQNNT ESSRLHCVLN
SNSTACGFAV GAGLLAFLTC LAFLALDTHE SRIGSSRFKT AFQLLDFILA VLWTGIWFVG
FCFLAHQWQH SPPEGLLLGS SSAKAAITFT FFSVLVWAFQ AYLALRDLRN DAPVPYKRSL
DEGGVALTTL SPPSAAGPVN TPPAGPNSLN YASSALSPYL ATPKAPRLAM MPDN
//
