ID M3VX12_FELCA Unreviewed; 724 AA.
AC M3VX12;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Tripartite motif containing 42 {ECO:0000313|Ensembl:ENSFCAP00000001531.3};
GN Name=TRIM42 {ECO:0000313|Ensembl:ENSFCAP00000001531.3,
GN ECO:0000313|VGNC:VGNC:102859};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000001531.3, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000001531.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001531.3,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000001531.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001531.3,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000001531.3}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001531.3};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AANG04001816; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003992100.1; XM_003992051.3.
DR AlphaFoldDB; M3VX12; -.
DR STRING; 9685.ENSFCAP00000001531; -.
DR PaxDb; 9685-ENSFCAP00000001531; -.
DR Ensembl; ENSFCAT00000001651.6; ENSFCAP00000001531.3; ENSFCAG00000001651.6.
DR GeneID; 101090205; -.
DR KEGG; fca:101090205; -.
DR CTD; 287015; -.
DR VGNC; VGNC:102859; TRIM42.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00530000064220; -.
DR HOGENOM; CLU_023245_0_0_1; -.
DR InParanoid; M3VX12; -.
DR OMA; FGNQQIY; -.
DR OrthoDB; 5383069at2759; -.
DR Proteomes; UP000011712; Chromosome C2.
DR Bgee; ENSFCAG00000001651; Expressed in testis.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00063; FN3; 1.
DR CDD; cd16578; RING-HC_TRIM42_C-III; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR017903; COS_domain.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR042765; TRIM42_RING-HC.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF255; TRIPARTITE MOTIF CONTAINING 42; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51262; COS; 1.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 146..192
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 285..326
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 434..492
FT /note="COS"
FT /evidence="ECO:0000259|PROSITE:PS51262"
FT DOMAIN 604..702
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
SQ SEQUENCE 724 AA; 82998 MW; 1582D97C0D68FF88 CRC64;
METAMCVCSP CCTWQRCCPQ LCSCLCCKFL FTSERNCTCF PCPYKDERNC QCCHCTCSEN
PNCHWCCCSW ANDPNCKCCC TTSSNLQCYY YESRCCRNAT ITFHKGRLRS IRTSSKTALR
IGSSDTQVDE VKTMPANSNL VHHLSCPLCH RLHLHSFMLP CNHSLCEKCL RQLQKHAEVT
ENFFILVCPV CSRSHCMPYS HKMQLPENYL RGRLTKRYMQ QHGYLKWRFD RSTGPTLCQV
CRSRRIAYKR CITCRLNLCN DCLKAFHSDV AMQDHVFVDT SSEDQDEKIC IHHPSSRIVE
YCSQDNQLLC TFCKTAFHNG HDTVNLIDAC SERAAALFSA IAKFKAVRYE IDNDLMEFNI
LKNSFKADKE MKRKEIRNGF LKLRNILQEK EKYIMEQLEN LEVSRQKEIE KYVYVTTMKV
NEMDGLIAYS KEALKETGQV AFLQSAKILV DQIEDGIQST FRPDPQLRLH SLHCMPLDFA
ELSSAIHELF PTGPKKVCSS GESLPSPYPM HSEMMISRKV TFSTHSFGNQ QIYQRSSSLL
SFNTTSGEKA KMGLEAYGRA QSATPAKPTD GLCTYWSAGA ENQPVQNSSS FHNWYSFNDD
SVKTPGPIVI YQTLVYPRAA KVYWTCPTED VDSFEMEFYE LVTTPPNNVQ TELCGQIRDI
MQQNLELHNL TPNTEYLFKV RAINNNGPGQ WSDICKVVTP DGHGKNRAKW GLLKNIQTAL
QKRF
//
