ID M3VXP6_FELCA Unreviewed; 753 AA.
AC M3VXP6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Semaphorin 3B {ECO:0000313|Ensembl:ENSFCAP00000001847.6};
GN Name=SEMA3B {ECO:0000313|Ensembl:ENSFCAP00000001847.6,
GN ECO:0000313|VGNC:VGNC:64986};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000001847.6, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000001847.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001847.6,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000001847.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001847.6,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000001847.6}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000001847.6};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; AANG04000016; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3VXP6; -.
DR PaxDb; 9685-ENSFCAP00000001847; -.
DR Ensembl; ENSFCAT00000001997.6; ENSFCAP00000001847.6; ENSFCAG00000001995.6.
DR VGNC; VGNC:64986; SEMA3B.
DR eggNOG; KOG3611; Eukaryota.
DR GeneTree; ENSGT00940000157756; -.
DR HOGENOM; CLU_009051_5_1_1; -.
DR Proteomes; UP000011712; Chromosome A2.
DR Bgee; ENSFCAG00000001995; Expressed in adult mammalian kidney and 10 other cell types or tissues.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF37; SEMAPHORIN-3B; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..753
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023823653"
FT DOMAIN 30..518
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 578..651
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 706..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 753 AA; 83901 MW; 3659211CEFE4B4F9 CRC64;
MGQAAAAAMI PGLALLWAAV LGGAAPSPPR LRLSFQELQD QHGLRTFRLE RTCCYEALLV
DEERGRLFVG AENRVASLSL DDISKRAKKL AWPAPVEWRE ECNWAGKDIG TECMNFVKLL
HAYNRTHLLA CGTGAFHPTC AFVEVGHRLE EPTLRLDLRR LEDGKGKSPY DPRHRAASVL
VGKELYSGVA ADLMGRDFTI FRSLGQRPSL RTEPHDSRWL NEPKFVKVFW IPESENPDDD
KIYFFFRESA VEASPSLGRQ TVSRVGQICR NDVGGQRSLV NKWTTFLKAR LVCSVPGVEG
DTHFDHLRFF PTEDMFLLSL RDRWSPLLYA VFSTSSTIFQ GSAVCVYSMN DVRRAFLGPF
AHKEGPMHQW VSYQGRVPYP RPGMCPSKTF GTFSSTKDFP DDVIQFARNH PLMYNSVLPM
GGRPLFIQVD AGYTFTQITA DRVAAADGHY DVLFIGTDAG TVLKVISVPK GSQPNGEGLL
LEELHVFEDS SAITSMQISS KRHQLYIASR SAVAQIPLHL CAAHGRACAE CCLARDPYCA
WDGAACTRFQ PSAKRRFRRQ DVRNGDPSTL CSGDSSHPAL LERKVFGVEG GSAFLECEPR
SLQARVEWTF QRAGEATHTQ VAMEERAERL TGGLLLRGLR RGDSGVYLCA AVEQGFSQSL
RRLVLHVLSA AQAERLARTE EAVPVAPPGP RLWYRDFLQL VEPGGGGASS LRMCRLQPES
RPPPPESRRK GRNRRRHAPE PRAERGPRSA AHW
//
