ID M3VZ31_FELCA Unreviewed; 464 AA.
AC M3VZ31;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Abhydrolase domain containing 15 {ECO:0000313|Ensembl:ENSFCAP00000002532.4};
GN Name=ABHD15 {ECO:0000313|Ensembl:ENSFCAP00000002532.4,
GN ECO:0000313|VGNC:VGNC:59480};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000002532.4, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000002532.4, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000002532.4,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000002532.4, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000002532.4,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000002532.4}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000002532.4};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC family. {ECO:0000256|ARBA:ARBA00010884}.
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DR EMBL; AANG04004035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3VZ31; -.
DR STRING; 9685.ENSFCAP00000002532; -.
DR ESTHER; felca-m3vz31; abh_upf0017.
DR PaxDb; 9685-ENSFCAP00000002532; -.
DR Ensembl; ENSFCAT00000002756.5; ENSFCAP00000002532.4; ENSFCAG00000002756.5.
DR VGNC; VGNC:59480; ABHD15.
DR eggNOG; KOG1838; Eukaryota.
DR GeneTree; ENSGT00950000182902; -.
DR HOGENOM; CLU_032487_3_0_1; -.
DR InParanoid; M3VZ31; -.
DR OMA; LPWLYER; -.
DR OrthoDB; 2944016at2759; -.
DR Proteomes; UP000011712; Chromosome E1.
DR Bgee; ENSFCAG00000002756; Expressed in liver and 8 other cell types or tissues.
DR GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR GO; GO:0034338; F:short-chain carboxylesterase activity; IBA:GO_Central.
DR GO; GO:0060612; P:adipose tissue development; IEA:Ensembl.
DR GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR GO; GO:0016042; P:lipid catabolic process; IEA:Ensembl.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR PANTHER; PTHR10794; ABHYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10794:SF39; PROTEIN ABHD15; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..464
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016394537"
FT REGION 32..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..56
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 51841 MW; 2A723EE9B518D08D CRC64;
MPPWGAALAL LLAALALLGL LAPRLRRAVG ARTLPGPRGR DHEEEVDGRG AADEFSDGRE
PLPGGCRLIC KPSALAQCLL SALRHSAALE PRPRSWLSGP HLQTLCHFVL PVGPGPELAR
EYLQLADDGL VALDWVVGPC PRGRRVTNAG GLPAVLLVIP NAWGRLTRNV LGLCLLALER
GYYPVIFHRR GHHGCPLVSP RLQPFGDPSD LKEAVTYIRF RHPAAPLFAV SEGSGSALLL
SYLGECGSSS YVTGAACISP VLRCREWFEA GLPWPYERGF LLHQKITLSR YASALQDTVD
THKLFRSRSL REFEETLFCH TKSFPISWDT YWDHNDPLRD VDEAAVPVLC ICSADDPVCG
PPDHFLPTEL FHSNPYFFLL LSHHGGHCGF LRQEPLPAWS HEVILEYFRA LTEFFRTEER
MKGLSRRRAS FLGGRRRWGT LQKREVSPSS HLEEIFSWKR SYTR
//
