GenomeNet

Database: UniProt
Entry: M3W1V9_FELCA
LinkDB: M3W1V9_FELCA
Original site: M3W1V9_FELCA 
ID   M3W1V9_FELCA            Unreviewed;       395 AA.
AC   M3W1V9;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   31-JUL-2019, entry version 44.
DE   RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN   Name=NHLRC1 {ECO:0000313|Ensembl:ENSFCAP00000003931,
GN   ECO:0000313|VGNC:VGNC:63796};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000003931, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000003931, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000003931,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000003931}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000003931};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000003931}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000003931};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AANG04001101; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003985798.1; XM_003985749.4.
DR   STRING; 9685.ENSFCAP00000003931; -.
DR   Ensembl; ENSFCAT00000004265; ENSFCAP00000003931; ENSFCAG00000004265.
DR   GeneID; 101099882; -.
DR   KEGG; fca:101099882; -.
DR   CTD; 378884; -.
DR   VGNC; VGNC:63796; NHLRC1.
DR   eggNOG; ENOG410ITF2; Eukaryota.
DR   eggNOG; ENOG410ZMHC; LUCA.
DR   GeneTree; ENSGT00730000111361; -.
DR   InParanoid; M3W1V9; -.
DR   KO; K10602; -.
DR   OrthoDB; 711255at2759; -.
DR   Proteomes; UP000011712; Chromosome B2.
DR   Bgee; ENSFCAG00000004265; Expressed in 3 organ(s), highest expression level in prefrontal cortex.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR   GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR   GO; GO:0006914; P:autophagy; IEA:Ensembl.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:Ensembl.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:Ensembl.
DR   GO; GO:0045859; P:regulation of protein kinase activity; IEA:Ensembl.
DR   GO; GO:1903076; P:regulation of protein localization to plasma membrane; IEA:Ensembl.
DR   GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:Ensembl.
DR   Gene3D; 2.120.10.30; -; 2.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013017; NHL_repeat_subgr.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF14634; zf-RING_5; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS51125; NHL; 6.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN       26     72       RING-type. {ECO:0000259|PROSITE:PS50089}.
SQ   SEQUENCE   395 AA;  42084 MW;  0291F9499227162B CRC64;
     MGTEASGSGP ALQELVREAE ISLLECKVCF ERFGHRQQRR PRNLPCGHVV CLACVAALAH
     PRTLALECPF CRRACRGCDT SDCLPVLHLL ELLGSALRPA PAAHRAAPSA PGAFTCHHVF
     GGWGTLVNPT GLALCPKTGR VVVAHDGRRR VKIFDSGGGC AHQFGEKGEG AQDIRYPLDV
     TVTNDCHVVV TDAGDRSIKV FDFFGQVKLV IGGQFSLPWG VETTPQNGVV VTDAEAGSLH
     LLEVDFPEGV LRRTEKLQVH LSNPRGVAVS WLTGAIAVLE HPPGLGTGAC GTTVKVFSPS
     MQLVGQVDTF GLSLFFPSRI TASAVTFDHQ GNVIVADTSS QAVLCLGKPE EFPVLKPMIT
     HGLSHPVALT FTKENSLLVL DSAAHSIKVY KADWG
//
DBGET integrated database retrieval system