ID M3WE38_FELCA Unreviewed; 441 AA.
AC M3WE38;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 24-JAN-2024, entry version 55.
DE RecName: Full=Sushi repeat containing protein X-linked {ECO:0008006|Google:ProtNLM};
GN Name=RPGR {ECO:0000313|Ensembl:ENSFCAP00000010104.5};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010104.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000010104.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010104.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000010104.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010104.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000010104.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010104.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AANG04002273; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WE38; -.
DR Ensembl; ENSFCAT00000010878.5; ENSFCAP00000010104.5; ENSFCAG00000030242.4.
DR eggNOG; ENOG502QVU2; Eukaryota.
DR GeneTree; ENSGT00940000159616; -.
DR HOGENOM; CLU_047011_0_0_1; -.
DR Proteomes; UP000011712; Chromosome X.
DR Bgee; ENSFCAG00000030242; Expressed in eyeball of camera-type eye and 10 other cell types or tissues.
DR CDD; cd00033; CCP; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR InterPro; IPR025232; DUF4174.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF1; SUSHI REPEAT-CONTAINING PROTEIN SRPX; 1.
DR Pfam; PF13778; DUF4174; 1.
DR Pfam; PF02494; HYR; 1.
DR Pfam; PF00084; Sushi; 3.
DR SMART; SM00032; CCP; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR PROSITE; PS50825; HYR; 1.
DR PROSITE; PS50923; SUSHI; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..441
FT /note="Sushi repeat containing protein X-linked"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016257435"
FT DOMAIN 44..94
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 95..153
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 152..236
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 237..296
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 124..151
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 267..294
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 441 AA; 49013 MW; 5F55C43FF52B08BD CRC64;
MGSSALRAAL LPLLPLLLLL RVPPSRAFPD TPWCSPIKVK YGDVYCRAPQ GGYYKTALGT
RCDIRCRKGY ELHGSSQLIC QSNRRWSDKV ICKQKRCPVL AMPANGGFKC VDGAYFNSRC
EYYCSPGYTL KGERTVTCMD NKAWSGRPAS CVDIEPPRIK CPSVKERIAE PNKLTVRVSW
ETPEGRDTAD GILTDVILKG LPPGSNFPEG DHKIQYTVYD RAENKGVCKF RVKVRVRRCG
KLNAPENGYM KCSSDGDNYG ATCEFSCIGG YELQGSPARV CQSNLAWSGT EPTCAAMNVN
VGVRTAAALL DQFYEKRRLL IVSTPTARNL LYRLQLGMLQ QAQCGLDLRH ITVVELVGVF
PTLIGRIGAK IMPPALALQL RLLLRIPLYS FSMVLVDKHG MDKERYVSLV MPVALFNLID
TFPLRKEEMV LQAEMGQTCN T
//
