ID M3WF47_FELCA Unreviewed; 514 AA.
AC M3WF47;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=Ankyrin repeat and death domain containing 1A {ECO:0000313|Ensembl:ENSFCAP00000010639.5};
GN Name=ANKDD1A {ECO:0000313|Ensembl:ENSFCAP00000010639.5,
GN ECO:0000313|VGNC:VGNC:59786};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010639.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000010639.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010639.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000010639.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010639.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000010639.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010639.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04001761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WF47; -.
DR STRING; 9685.ENSFCAP00000010639; -.
DR Ensembl; ENSFCAT00000011455.6; ENSFCAP00000010639.5; ENSFCAG00000011452.6.
DR VGNC; VGNC:59786; ANKDD1A.
DR eggNOG; KOG4177; Eukaryota.
DR GeneTree; ENSGT00940000154170; -.
DR HOGENOM; CLU_000134_51_1_1; -.
DR InParanoid; M3WF47; -.
DR OMA; RFYKWEQ; -.
DR Proteomes; UP000011712; Chromosome B3.
DR Bgee; ENSFCAG00000011452; Expressed in prefrontal cortex and 9 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR PANTHER; PTHR24125; ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24125:SF0; ANKYRIN REPEAT AND DEATH DOMAIN-CONTAINING PROTEIN 1A; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 3.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 11.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 7.
DR PROSITE; PS50088; ANK_REPEAT; 8.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 47..79
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 85..117
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 153..185
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 186..218
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 219..251
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 252..284
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 285..317
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 318..350
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 427..501
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
SQ SEQUENCE 514 AA; 57116 MW; 742FAADF0ADFAF5B CRC64;
MEEPAAWEND GLLPLERQLH EAARRNNIRR MKELIERKVD IRARNHVGRA ALHWAAGAGH
EQAVRLLLEH EVAVDDEDAV GDPSFGMNSL LLSAWFGHLQ ILQILVNSGA KIHCKNKDGL
TLLHCAAQKG HVPVLAFIME DLEDVPLDQA DKLGRTAFHR AAEHGQLDAL DFLVGSGCEH
SVKDKEGNTA LHLAASRGHL TVLQRLVDIR LDLEEQNVEG LTALHAAVEG SHPDCVQLLL
EAGSSVNALT QKKQSCLHYA ALGGSEDVAR ALIHAGGHTN IADHQGASPM HLAVRHNFPA
LVQLLIDAGS DLDATDNRQQ TPLHLAAEHA WQDIAEMLLV TGVNLNLRDK QGKTALAVAA
RSNHISLVDM IIKADRLYKW EKDHVLCRDP RDPSGKNLTF KQDHRQETQQ FHSVLWRLAS
RHLRPQEWKK LAYCWEFTEA HVHAIEQQWT GIKSYQEHGH RMLLIWLHGV AIAGENPNKA
LFEGLVAIGR RDLAESIRKK ANADPGTPRR CTAM
//
