ID M3WFP1_FELCA Unreviewed; 229 AA.
AC M3WFP1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 24-JAN-2024, entry version 61.
DE RecName: Full=Synaptogyrin {ECO:0000256|PIRNR:PIRNR011282};
GN Name=SYNGR3 {ECO:0000313|Ensembl:ENSFCAP00000010900.5,
GN ECO:0000313|VGNC:VGNC:80687};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010900.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000010900.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010900.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000010900.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010900.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000010900.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010900.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|PIRNR:PIRNR011282}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|PIRNR:PIRNR011282}.
CC -!- SIMILARITY: Belongs to the synaptogyrin family.
CC {ECO:0000256|ARBA:ARBA00010252, ECO:0000256|PIRNR:PIRNR011282}.
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DR EMBL; AANG04000231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WFP1; -.
DR STRING; 9685.ENSFCAP00000010900; -.
DR PaxDb; 9685-ENSFCAP00000010900; -.
DR Ensembl; ENSFCAT00000011746.6; ENSFCAP00000010900.5; ENSFCAG00000011743.6.
DR VGNC; VGNC:80687; SYNGR3.
DR eggNOG; KOG4016; Eukaryota.
DR GeneTree; ENSGT00950000182935; -.
DR HOGENOM; CLU_079186_1_0_1; -.
DR InParanoid; M3WFP1; -.
DR OMA; RVTTWIF; -.
DR OrthoDB; 4177492at2759; -.
DR Proteomes; UP000011712; Chromosome E3.
DR Bgee; ENSFCAG00000011743; Expressed in prefrontal cortex and 5 other cell types or tissues.
DR GO; GO:0031594; C:neuromuscular junction; IBA:GO_Central.
DR GO; GO:0030672; C:synaptic vesicle membrane; IBA:GO_Central.
DR GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
DR GO; GO:0045055; P:regulated exocytosis; IEA:Ensembl.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR016579; Synaptogyrin.
DR PANTHER; PTHR10838; SYNAPTOGYRIN; 1.
DR PANTHER; PTHR10838:SF8; SYNAPTOGYRIN-3; 1.
DR Pfam; PF01284; MARVEL; 1.
DR PIRSF; PIRSF011282; Synaptogyrin; 1.
DR PROSITE; PS51225; MARVEL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR011282, ECO:0000256|PROSITE-
KW ProRule:PRU00581}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|PIRNR:PIRNR011282, ECO:0000256|PROSITE-
KW ProRule:PRU00581}; Transmembrane helix {ECO:0000256|PIRNR:PIRNR011282}.
FT TRANSMEM 26..44
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 64..88
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 109..128
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000256|PIRNR:PIRNR011282"
FT DOMAIN 20..172
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT REGION 209..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 229 AA; 24491 MW; 02D2415FB0922FA3 CRC64;
MEGASFGAGR AGAALDPVSF ARRPQTLLRV VSWVFSIAVF GPIVNEGYVN TDSGPELRCV
FNGNAGACRF GVALGLGAFL ACAAFLLLDV RFQQISSVRD RRRAVLLDLG FSGLWSFLWF
VGFCFLTNQW QRTAPGPGTL QAGDAARAAI AFSFFSILSW VALTVKALQR FRLGTDMSLF
ATEQLGAGAG QAYPGYPVGS GVEGTETYQS PPFTETLDTS PKGYQVPAY
//
