ID M3WFR1_FELCA Unreviewed; 203 AA.
AC M3WFR1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 3.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=CD3 epsilon subunit of T-cell receptor complex {ECO:0000313|Ensembl:ENSFCAP00000010930.4};
GN Name=CD3E {ECO:0000313|VGNC:VGNC:81992};
GN Synonyms=CD3G {ECO:0000313|Ensembl:ENSFCAP00000010930.4};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000010930.4, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000010930.4, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010930.4,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000010930.4, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010930.4,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000010930.4}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000010930.4};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04000369; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WFR1; -.
DR PaxDb; 9685-ENSFCAP00000010930; -.
DR Ensembl; ENSFCAT00000011779.5; ENSFCAP00000010930.4; ENSFCAG00000011773.6.
DR VGNC; VGNC:81992; CD3E.
DR eggNOG; ENOG502S4XC; Eukaryota.
DR GeneTree; ENSGT00940000153312; -.
DR HOGENOM; CLU_115449_0_0_1; -.
DR Proteomes; UP000011712; Chromosome D1.
DR Bgee; ENSFCAG00000011773; Expressed in spleen and 9 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR015484; CD3_esu/gsu/dsu.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032052; Ig_4.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR10570:SF8; T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN; 1.
DR PANTHER; PTHR10570; T-CELL SURFACE GLYCOPROTEIN CD3 GAMMA CHAIN / DELTA CHAIN; 1.
DR Pfam; PF16680; Ig_4; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..203
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5023887005"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..94
FT /note="Immunoglobulin subtype 2"
FT /evidence="ECO:0000259|SMART:SM00408"
SQ SEQUENCE 203 AA; 22687 MW; 3DC485570E62BF58 CRC64;
MEQGKQLAGL ILAVTLLQGT LAQSKQEIPV VRVNSDREDG SVLLTCESPD KDVKWFQDGK
EMTPHKKNKN IQNLGSSIKD PRGIYWCQGS KNRSRTLQVY FRMCQNCIEL SGATVSGFVF
TEIISVFFLA VGVYFIAGQD GVRQSRASDK QTLLSNDQLY QVREGEVKET LLQFGVKFGG
GGDKLFGGYR TDKELLRAYQ MIT
//
