ID M3WHA4_FELCA Unreviewed; 1076 AA.
AC M3WHA4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Glutamate receptor interacting protein 1 {ECO:0000313|Ensembl:ENSFCAP00000011714.6};
GN Name=GRIP1 {ECO:0000313|Ensembl:ENSFCAP00000011714.6,
GN ECO:0000313|VGNC:VGNC:62714};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000011714.6, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000011714.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000011714.6,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000011714.6, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000011714.6,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000011714.6}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000011714.6};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WHA4; -.
DR Ensembl; ENSFCAT00000012633.6; ENSFCAP00000011714.6; ENSFCAG00000012630.6.
DR VGNC; VGNC:62714; GRIP1.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00940000158692; -.
DR HOGENOM; CLU_004313_0_0_1; -.
DR Proteomes; UP000011712; Chromosome B4.
DR Bgee; ENSFCAG00000012630; Expressed in testis and 9 other cell types or tissues.
DR CDD; cd00992; PDZ_signaling; 7.
DR Gene3D; 2.30.42.10; -; 7.
DR InterPro; IPR043545; GRIP1/2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR46227:SF3; GLUTAMATE RECEPTOR-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR46227; GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP; 1.
DR Pfam; PF00595; PDZ; 6.
DR Pfam; PF17820; PDZ_6; 1.
DR SMART; SM00228; PDZ; 7.
DR SUPFAM; SSF50156; PDZ domain-like; 7.
DR PROSITE; PS50106; PDZ; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 53..136
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 150..238
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 252..336
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 420..495
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 521..606
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 621..703
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 952..1034
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 706..747
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..831
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 883..929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..831
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1076 AA; 116254 MW; C84C2E86E906DEDF CRC64;
MIAVSFKCRC QILRRLAKDE SPYTKSASQT KPPDGALAVR RQSIPEEFKG STVVELMKKE
GTTLGLTVSG GIDKDGKPRV SNLRQGGIAA RSDQLDVGDY IKAVNGINLA KFRHDEIISL
LKNVGERVVL EVEYELPPVS VQGSSVIFRT VEVTLHKEGN TFGFVIRGGA HDDRNKSRPV
VITCVRPGGP ADREGTIKPG DRLLSVDGIR LLGTTHAEAM SILKQCGQEA TLLIEYDVSV
MDSVATASGP LLVEVAKTPG ASLGVALTTS MCCNKQVIVI DKIKSASIAD RCGALHVGDH
ILSIDGTSME YCTLAEATQF LANTTDQVKL EILPHHQTRL ALKGPEHAAL VSSPFSPTSM
SAYSLSSLNM GTLPRSLYST SPRGTMMRRR LKKKDFKSSL SLASSTVGLA GQVVHTETTE
VVLTADPVTG FGIQLQGSVF ATETLSSPPL ISYIEADSPA ERCGVLQIGD RVIAINGIPT
EDSTFEEANQ LLRDSSITSK VTLEIEFDVA ESVIPSSGTF HVKLPKKHNV ELGITISSPS
SRKPGDPLVI SDIKKGSVAH RTGTLELGDK LLAIDNIRLD NCSMEDAVQI LQQCEDLVKL
KIRKDEDNSD EQESSGAIIY TVELKRYGGP LGITISGTEE PFDPIIISSL TKGGLAERTG
AIHIGDRILA INSSSLKGKP LSEAIHLLQM AGETVTLKIK KQTDAQAASS PKKFPISSHL
SDLGDVEEDP SLAQKPGKLT DTYPSTVPSV DSAVDSWDGS GIDSGYGNQG SGFQASGYSF
NTYEWRGPKQ RGSLSPVTKP RSQTYPDVGL SNEDWDRSTV SGFTGAPDST EAEQEENFWS
QALEDLETCG QSGILRELEE KADRRVSLRN MTLLATIMSG STMSLNHEAP TPRSQLGRQA
SFQERSSSRP HYSQTTRSNT LPSDVGRKSV TLRKMKQEIK EIMSPTPVEL HKVTLYKSSD
VEDFGFSVAD GLLEKGVYVK NIRPAGPGDL GGLKPYDRLL QVNHVRTRDF DCCLVVPLIA
ESGNKLDLVI SRNPLASQKS IEQTLPGGEW SEQNSAFFQQ PSHGSNLEIR EPTNTL
//
