ID M3WIR5_FELCA Unreviewed; 602 AA.
AC M3WIR5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Methyltransferase like 25 {ECO:0000313|Ensembl:ENSFCAP00000033697.1};
GN Name=METTL25 {ECO:0000313|Ensembl:ENSFCAP00000033697.1,
GN ECO:0000313|VGNC:VGNC:63464};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000033697.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000033697.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000033697.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000033697.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000033697.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000033697.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000033697.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003655; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003989134.1; XM_003989085.3.
DR AlphaFoldDB; M3WIR5; -.
DR STRING; 9685.ENSFCAP00000033697; -.
DR PaxDb; 9685-ENSFCAP00000012406; -.
DR Ensembl; ENSFCAT00000039514.3; ENSFCAP00000033697.1; ENSFCAG00000013377.6.
DR GeneID; 101093369; -.
DR KEGG; fca:101093369; -.
DR CTD; 84190; -.
DR VGNC; VGNC:63464; METTL25.
DR eggNOG; KOG2651; Eukaryota.
DR GeneTree; ENSGT00530000063745; -.
DR HOGENOM; CLU_016581_2_0_1; -.
DR InParanoid; M3WIR5; -.
DR OMA; CCYHLLR; -.
DR OrthoDB; 3060170at2759; -.
DR Proteomes; UP000011712; Chromosome B4.
DR Bgee; ENSFCAG00000013377; Expressed in liver and 11 other cell types or tissues.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12496; CGI-41 METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12496:SF9; METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED; 1.
DR Pfam; PF13679; Methyltransf_32; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712}.
FT DOMAIN 154..230
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13679"
FT DOMAIN 338..418
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13679"
SQ SEQUENCE 602 AA; 68145 MW; 6167468A876C3D03 CRC64;
MAASFPLPVT QDLSTLRAKL QGLLQFLRQA LSISSAHTVD FYTESVWKQL VDLPPETALR
VLRRSAAEAE ARSPEARLLV EAEMGSGIAS FPQIFCETSQ KLVSVEAFAL AVRYYSVQNL
GICTPFEQLL TALRGNQKQR TGENVKPDEF MNLKKSHEVQ VMSELISSIA DYCGIKQVID
LGSGKGYLSS FLSLKYGLKV YGIDSSNTNT HGAKERNRKL KKHWKVYHTR SKLDGNGLAL
KMAKERKVQD EIKYKVDIEG ICNNSPANQG KMSTSDFLPD FSDSVISNIR TQMENLHVYS
HREENLCFEN AFSLIDLLPI NAVEPTSLQT SKRNMSEANK ERRKMISKSN ESNIYSPLTS
FITADSELHD IIKDLEDCLM VGLHTCGDLA PNTLRIFTSQ PEIKGVCSVG CCYHLLSEEF
ENLHKESTQD KWGFPMCHYL KEERWCCGRN ARMSACLALE RVAVGQGLPT ESLFYRAVLQ
DIIKECYGIT KCDRHVGKIY SKSSSFLDYA RKSLKKLGLD ESKLPEKVIM DYYEKYKPRM
NELEAFNMLK VVLAPCIETL ILLDRLCYLK EQENIAWSAL VKLFDPVKSP RCYAIIALKK
QQ
//
