ID M3WIU0_FELCA Unreviewed; 875 AA.
AC M3WIU0;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 3.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Solute carrier family 4 member 11 {ECO:0000313|Ensembl:ENSFCAP00000012445.5};
GN Name=SLC4A11 {ECO:0000313|Ensembl:ENSFCAP00000012445.5,
GN ECO:0000313|VGNC:VGNC:65385};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000012445.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000012445.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012445.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000012445.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012445.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000012445.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012445.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993}.
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DR EMBL; AANG04003379; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WIU0; -.
DR Ensembl; ENSFCAT00000013422.6; ENSFCAP00000012445.5; ENSFCAG00000013416.6.
DR VGNC; VGNC:65385; SLC4A11.
DR eggNOG; KOG1172; Eukaryota.
DR GeneTree; ENSGT00940000154894; -.
DR HOGENOM; CLU_002289_6_0_1; -.
DR Proteomes; UP000011712; Chromosome A3.
DR Bgee; ENSFCAG00000013416; Expressed in eyeball of camera-type eye and 10 other cell types or tissues.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF82; SOLUTE CARRIER FAMILY 4 MEMBER 11; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..469
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 560..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..617
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..660
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..704
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..788
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 815..834
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 840..858
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 327..820
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
SQ SEQUENCE 875 AA; 98075 MW; 847C83A4F56B70B7 CRC64;
MAAATRRLFH LQPCESSSEM SQNGFVEDVV GYLKCDMDDA SETREENLGD EAFDTVTSSI
VSGESIRFFV NVNLEVQPAQ AAESESPGGC GLLHTSRKYL KLKNFEEEVR AHRDLDGFLA
RASIILNETA TSLDDVLRAM LSRLAHDPHN TEPDCNLRLF MAMLFTDAGA PMEGKAHLLS
DTIQGVTATA TGVQYQQSWI CIICTSKALQ KRHVCISRLV RPQNWGENSC EVRFVILVLA
PPKMKSTKTA AEVGRTFATM FLDITFRQKL LNTRTEEEFK EALVHQRQLL TMERQRSSIG
TKGYMNSISI HKSPQPPKHK DFLPMGKGIR EDIARRFPVY PLDFTDGIIG KNKAVGKYIT
TTLFLYFACL LPTIAFGSLN DENTNGAIDV QKTIAGQSIG GLLYALFSGQ PLVVLLTTAP
LALYIQVISG ICDDYDLDFN TFYAWTGLWN SFFLALYSLF NLSLLMSLFK RSTEEIIALF
ISITFMLDAV KGMVKIFQKY YYDNFGNHHE DNTSTVSLLG LGTSLNTSLH TALNTSLLAS
PLELTSVSGP GTEHPGRETA VLSLLIMLGT LWLSYTLYQF KKSPYLHPYM REILSDCALP
ISVLTFSLIC SYGFREIKMS QFRYNPSKSL FEVAEMHSLS LGAVTSAMGL GFLLSLLFFI
EQNLVAALAN APENRLVKGT AYHWDLLLIA IINSGLSLFG LPWIHAAYPH SPLHVRALAM
VEERVENGHI YETIVNVKET RLTTLGASIL VGFSLLLLPF PLQWIPKPVL YGLFLYIALT
SIDGNQLFER VALLLKDQTS YPPTHYIRRV PQRKIHYFTG LQVMQLLLLC AFGMSNLPYM
KMIFPLIMIV MIPIRYNLLP RIIEAKYLDV MDAEH
//
