ID M3WJA6_FELCA Unreviewed; 403 AA.
AC M3WJA6;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 4.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Synaptotagmin 7 {ECO:0000313|Ensembl:ENSFCAP00000012688.5};
GN Name=SYT7 {ECO:0000313|Ensembl:ENSFCAP00000012688.5,
GN ECO:0000313|VGNC:VGNC:65902};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000012688.5, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000012688.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012688.5,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000012688.5, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012688.5,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000012688.5}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000012688.5};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the synaptotagmin family.
CC {ECO:0000256|ARBA:ARBA00006996}.
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DR EMBL; AANG04000779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WJA6; -.
DR Ensembl; ENSFCAT00000013684.5; ENSFCAP00000012688.5; ENSFCAG00000013680.5.
DR VGNC; VGNC:65902; SYT7.
DR eggNOG; KOG1028; Eukaryota.
DR GeneTree; ENSGT00940000157180; -.
DR HOGENOM; CLU_023008_7_2_1; -.
DR Proteomes; UP000011712; Chromosome D1.
DR Bgee; ENSFCAG00000013680; Expressed in prefrontal cortex and 10 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:InterPro.
DR CDD; cd08386; C2A_Synaptotagmin-7; 1.
DR CDD; cd08405; C2B_Synaptotagmin-7; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037732; C2A_Synaptotagmin-7.
DR InterPro; IPR037741; C2B_Synaptotagmin-7.
DR InterPro; IPR001565; Synaptotagmin.
DR PANTHER; PTHR10024; SYNAPTOTAGMIN; 1.
DR PANTHER; PTHR10024:SF344; SYNAPTOTAGMIN-7; 1.
DR Pfam; PF00168; C2; 2.
DR PRINTS; PR00360; C2DOMAIN.
DR PRINTS; PR00399; SYNAPTOTAGMN.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 135..255
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 266..399
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 53..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 45515 MW; E07D6D74DB3004E8 CRC64;
MYRDPEAASP GAPTRDVLLV SAIITVSLSV TVVLCGLCHW CQRKLGKRYK NSLETVGTPD
SGRGRSEKKA IKLPAGGKAV NTAPVPGQTP HDESDRRTEP RSSVSDLVNS LTSEMLMLSP
GSEEDEAHEG CSRDNLGRIQ FSVGYNFQES TLTVKIMRAQ ELPAKDFSGT SDPFVKIYLL
PDKKHKLETK VKRKNLNPHW NETFLFEGFP YEKVVQRVLY LQVLDYDRFS RNDPIGEVSI
PLNKVDLTQM QTFWKDLKPC SDGSGSRGEL LLSLCYNPSA NSIIVNIIKA RNLKAMDIGG
TSDPYVKVWL MYKDKRVEKK KTVTMKRNLN PIFNESFAFD IPTEKLRETT IIITVMDKDK
LSRNDVIGKI YLSWKSGPGE VKHWKDMIAR PRQPVAQWHQ LKA
//
