ID M3WKJ7_FELCA Unreviewed; 634 AA.
AC M3WKJ7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 24-JAN-2024, entry version 72.
DE SubName: Full=Kelch like family member 31 {ECO:0000313|Ensembl:ENSFCAP00000013315.2};
GN Name=KLHL31 {ECO:0000313|Ensembl:ENSFCAP00000013315.2,
GN ECO:0000313|VGNC:VGNC:63153};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000013315.2, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000013315.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000013315.2,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000013315.2, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000013315.2,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000013315.2}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000013315.2};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AANG04003966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006931864.1; XM_006931802.3.
DR AlphaFoldDB; M3WKJ7; -.
DR PaxDb; 9685-ENSFCAP00000013315; -.
DR Ensembl; ENSFCAT00000014357.5; ENSFCAP00000013315.2; ENSFCAG00000014353.5.
DR GeneID; 102902433; -.
DR KEGG; fca:102902433; -.
DR CTD; 401265; -.
DR VGNC; VGNC:63153; KLHL31.
DR eggNOG; KOG4441; Eukaryota.
DR GeneTree; ENSGT00940000158352; -.
DR HOGENOM; CLU_004253_14_3_1; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000011712; Chromosome B2.
DR Bgee; ENSFCAG00000014353; Expressed in adult mammalian kidney and 7 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0001933; P:negative regulation of protein phosphorylation; IEA:InterPro.
DR CDD; cd18470; BACK_KLHL31_KBTBD1; 1.
DR CDD; cd18260; BTB_POZ_KLHL31_KBTBD1; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030604; BTB_POZ_KLHL31.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF17; KELCH-LIKE PROTEIN 31; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..137
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 634 AA; 70164 MW; B41F393A655F90C2 CRC64;
MAPKKKTVKK NKGDINEMTI IVEDSPLNKL NALNGLLEGG NGLNCISSEL TDASYGPNLL
EGLSRMRQEN FLCDLVIGTK TKSFDVHKSV MASCSEYFYN ILKKDPSTQR VDLNDISPLG
LATVIAYAYT GKLTLSLYTI GSIISAAVYL QIHTLVKMCS DFLIREMSVE NCMYIANIAE
TYSLKNAKAA TQKFIRDNFL EFAESDQFLK LTFEQINELL IDDDLQLPSE IVAFQIAMKW
LEFDQKRVRY AADLLSNIRF GTISAQDLVN YVQSVPRMMQ DADCHKLLVD AMNYHLLPYH
QNTLQSRRTR IRGGCRVLVT VGGRPGLTEK SLSRDILYRD PENGWSKLTE MPAKSFNQCV
AVMDGFLYVA GGEDQNDARN QAKHAVSNFC RYDPRFNTWI HLASMNQKRT HFSLSVFNGL
LYAVGGRNTE GSLASLECYV PSTNQWQPKT PLEVARCCHA SAVTDGRVLV TGGYIGNAYS
RSVCAYDPAG DSWQELPGLS TPRGWHCAVT LGDRVYVMGG SQLGARGERV DVLTVECFSP
ATGQWSYAAP LLVGVSTAGA SALHGRAYLV GGWNEGEKKY KKCIQCFSPE LNEWMEDDEL
PEATVGVSCC TLSMPNSVTR ESRASSVSSV PVSI
//
