ID M3WMJ3_FELCA Unreviewed; 401 AA.
AC M3WMJ3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 10-OCT-2018, sequence version 2.
DT 24-JAN-2024, entry version 59.
DE RecName: Full=Myeloid-associated differentiation marker-like protein 2 {ECO:0000256|ARBA:ARBA00040733};
GN Name=MYADML2 {ECO:0000313|Ensembl:ENSFCAP00000014285.3,
GN ECO:0000313|VGNC:VGNC:63669};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000014285.3, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000014285.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000014285.3,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000014285.3, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000014285.3,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000014285.3}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000014285.3};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MAL family. {ECO:0000256|ARBA:ARBA00034721}.
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DR EMBL; AANG04004184; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3WMJ3; -.
DR STRING; 9685.ENSFCAP00000014285; -.
DR PaxDb; 9685-ENSFCAP00000014285; -.
DR Ensembl; ENSFCAT00000015410.4; ENSFCAP00000014285.3; ENSFCAG00000015406.4.
DR VGNC; VGNC:63669; MYADML2.
DR eggNOG; KOG4788; Eukaryota.
DR GeneTree; ENSGT00950000182933; -.
DR HOGENOM; CLU_068368_0_0_1; -.
DR InParanoid; M3WMJ3; -.
DR OMA; HLSWGNF; -.
DR Proteomes; UP000011712; Chromosome E1.
DR Bgee; ENSFCAG00000015406; Expressed in prefrontal cortex and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR047123; MYADM-like.
DR PANTHER; PTHR17068; MYELOID-ASSOCIATED DIFFERENTIATION MARKER MYADM FAMILY MEMBER; 1.
DR PANTHER; PTHR17068:SF5; MYELOID-ASSOCIATED DIFFERENTIATION MARKER-LIKE PROTEIN 2; 1.
DR Pfam; PF01284; MARVEL; 2.
DR PROSITE; PS51225; MARVEL; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00581}; Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00581};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 149..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..242
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 111..248
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT DOMAIN 253..397
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT REGION 67..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 401 AA; 42127 MW; 23A6A8B9B6622D69 CRC64;
MGTGTPGLLF RGSNRDHLFI VLGGGGALAR PTRAAARLSC GNVKAAAAAA AAASRLLQAA
GTCHGCRRRQ RGRSPAGTPA PAGTVRGEDD VAGQMGSTME PPGGGYLHLG AVTSPVGTAR
VLQLAFGCTT FSLVAHRGGF AGVQGTFCVA AWGFCFALSG LVVACEFTRL HSCLHLSWGN
FTAAFAMLAT LLSATAAVIY PLYFTRLECP PEPAGCAARD FRLAASVFAG LLFLAYAAEV
ALTRARPGQV ASYMATVSGL LKIVQAFVAC IIFGALVYDS RYGRYVATQW CVAVYSLCFL
ATVAVVVLSV TGHTGGLGCP FDRLVVVYTF LAVLLYLSAA VIWPVFCFDP KYGEPGRPPD
CPRGGCFWDS QLVVATFTYV NLLLYVADLA YSQRIRFVPP L
//
