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Database: UniProt
Entry: M3XB25_FELCA
LinkDB: M3XB25_FELCA
Original site: M3XB25_FELCA 
ID   M3XB25_FELCA            Unreviewed;       517 AA.
AC   M3XB25;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 2.
DT   28-MAR-2018, entry version 40.
DE   SubName: Full=Potassium voltage-gated channel subfamily A member 3 {ECO:0000313|Ensembl:ENSFCAP00000023829};
GN   Name=KCNA3 {ECO:0000313|Ensembl:ENSFCAP00000023829};
OS   Felis catus (Cat) (Felis silvestris catus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
OC   Felinae; Felis.
OX   NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000023829, ECO:0000313|Proteomes:UP000011712};
RN   [1] {ECO:0000313|Ensembl:ENSFCAP00000023829, ECO:0000313|Proteomes:UP000011712}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000023829,
RC   ECO:0000313|Proteomes:UP000011712};
RX   PubMed=17975172; DOI=10.1101/gr.6380007;
RA   Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA   Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
RA   Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
RA   Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
RA   Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
RT   "Initial sequence and comparative analysis of the cat genome.";
RL   Genome Res. 17:1675-1689(2007).
RN   [2] {ECO:0000313|Ensembl:ENSFCAP00000023829}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000023829};
RA   Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT   "Sequence assembly of the Felis catus genome version 6.2.";
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSFCAP00000023829}
RP   IDENTIFICATION.
RC   STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000023829};
RG   Ensembl;
RL   Submitted (MAR-2013) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
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DR   EMBL; AANG03320165; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AANG03320166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9685.ENSFCAP00000023829; -.
DR   Ensembl; ENSFCAT00000024587; ENSFCAP00000023829; ENSFCAG00000030328.
DR   eggNOG; KOG1545; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00760000118846; -.
DR   InParanoid; M3XB25; -.
DR   OMA; LPRRDFQ; -.
DR   OrthoDB; EOG091G10NU; -.
DR   Proteomes; UP000011712; Chromosome C1.
DR   Bgee; ENSFCAG00000030328; -.
DR   GO; GO:0030424; C:axon; IEA:Ensembl.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IBA:GO_Central.
DR   GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.350; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR   InterPro; IPR003972; K_chnl_volt-dep_Kv1.
DR   InterPro; IPR004050; K_chnl_volt-dep_Kv1.3.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   InterPro; IPR028325; VG_K_chnl.
DR   InterPro; IPR027359; Volt_channel_dom_sf.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF02214; BTB_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01510; KV13CHANNEL.
DR   PRINTS; PR01491; KVCHANNEL.
DR   PRINTS; PR01496; SHAKERCHANEL.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000011712};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00085096, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00084820,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00084701,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268};
KW   Voltage-gated channel {ECO:0000256|SAAS:SAAS00984201}.
FT   TRANSMEM    178    198       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    237    257       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    340    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    401    422       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       46    146       BTB. {ECO:0000259|SMART:SM00225}.
SQ   SEQUENCE   517 AA;  58153 MW;  4F09BCD336BA1C72 CRC64;
     KVERVSSELE REQMHGCVQG GGCDRDRYEP LPPALPAAGE QDCCGERVVI NISGLRFETQ
     LKTLCQFPET LLGDPKRRMR YFDPLRNEYF FDRNRPSFDA ILYYYQSGGR IRRPVNVPID
     IFSEEIRFYQ LGEEAMEKFR EDEGFLREEE RPLPRHDFQR QVWLLFEYPE SSGPARGIAI
     VSVLVILISI VIFCLETLPE FRDEKDYPAA SSQEQFEAAG NSTSGAPAGA SSFSDPFFVV
     ETLCIIWFSF ELLVRFFACP SKATFSRNIM NLIDIVAIIP YFITLGTELA ERQGNGQQAM
     SLAILRVIRL VRVFRIFKLS RHSKGLQILG QTLKASMREL GLLIFFLFIG VILFSSAVYF
     AEADDPTSGF SSIPDAFWWA VVTMTTVGYG DMHPVTIGGK IVGSLCAIAG VLTIALPVPV
     IVSNFNYFYH RETEGEEQAQ YMHVGSCQHL SSSAEELRKA RSNSTLSKSE YMVIEEGGMN
     HSAFPQTPFK TGNSTAPCTT NNNPNSCVNI KKIFTDV
//
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