ID M3XEL8_FELCA Unreviewed; 218 AA.
AC M3XEL8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Proline rich and Gla domain 1 {ECO:0000313|Ensembl:ENSFCAP00000025076.1};
GN Name=PRRG1 {ECO:0000313|Ensembl:ENSFCAP00000025076.1,
GN ECO:0000313|VGNC:VGNC:69084};
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685 {ECO:0000313|Ensembl:ENSFCAP00000025076.1, ECO:0000313|Proteomes:UP000011712};
RN [1] {ECO:0000313|Ensembl:ENSFCAP00000025076.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000025076.1,
RC ECO:0000313|Proteomes:UP000011712};
RX PubMed=17975172; DOI=10.1101/gr.6380007;
RA Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
RA Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N., Schaffer A.A.,
RA Agarwala R., Narfstrom K., Murphy W.J., Giger U., Roca A.L., Antunes A.,
RA Menotti-Raymond M., Yuhki N., Pecon-Slattery J., Johnson W.E., Bourque G.,
RA Tesler G., O'Brien S.J.;
RT "Initial sequence and comparative analysis of the cat genome.";
RL Genome Res. 17:1675-1689(2007).
RN [2] {ECO:0000313|Ensembl:ENSFCAP00000025076.1, ECO:0000313|Proteomes:UP000011712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000025076.1,
RC ECO:0000313|Proteomes:UP000011712};
RA Hillier L.W., Warren W., Obrien S., Wilson R.K.;
RT "Sequence assembly of the Felis catus genome version 6.2.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSFCAP00000025076.1}
RP IDENTIFICATION.
RC STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000025076.1};
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR EMBL; AANG04003539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004000442.1; XM_004000393.4.
DR RefSeq; XP_019679283.1; XM_019823724.1.
DR RefSeq; XP_019679284.1; XM_019823725.1.
DR AlphaFoldDB; M3XEL8; -.
DR PaxDb; 9685-ENSFCAP00000025076; -.
DR Ensembl; ENSFCAT00000032213.4; ENSFCAP00000025076.1; ENSFCAG00000022973.4.
DR GeneID; 101085954; -.
DR KEGG; fca:101085954; -.
DR CTD; 5638; -.
DR VGNC; VGNC:69084; PRRG1.
DR eggNOG; ENOG502RU75; Eukaryota.
DR GeneTree; ENSGT00940000158538; -.
DR HOGENOM; CLU_103591_0_0_1; -.
DR OrthoDB; 5356014at2759; -.
DR Proteomes; UP000011712; Chromosome X.
DR Bgee; ENSFCAG00000022973; Expressed in brain and 10 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 4.10.740.10; Coagulation Factor IX; 1.
DR InterPro; IPR017857; Coagulation_fac-like_Gla_dom.
DR InterPro; IPR035972; GLA-like_dom_SF.
DR InterPro; IPR000294; GLA_domain.
DR PANTHER; PTHR24278; COAGULATION FACTOR; 1.
DR PANTHER; PTHR24278:SF37; TRANSMEMBRANE GAMMA-CARBOXYGLUTAMIC ACID PROTEIN 1; 1.
DR Pfam; PF00594; Gla; 1.
DR PRINTS; PR00001; GLABLOOD.
DR SMART; SM00069; GLA; 1.
DR SUPFAM; SSF57630; GLA-domain; 1.
DR PROSITE; PS00011; GLA_1; 1.
DR PROSITE; PS50998; GLA_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011712};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..66
FT /note="Gla"
FT /evidence="ECO:0000259|PROSITE:PS50998"
FT REGION 161..192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24981 MW; F0A3694A467329FF CRC64;
MGRIFLTGEK ANSVLKRYPR ANGLFEEIRQ GNIERECKEE ICTFEEAREA FENNEKTKEF
WNTYTKAQQG ESNRGSDWFQ FYLTFPLIFG LFIILLVIFL IWRCFLRNKT RRQTVTEGHI
PFPQHLNIIT PPPPPDEVFD SSGLSPGFLE YVVGRSDSVS TRLSNCDPPP TYEEATGQVT
LRRSETEPHL DPPPEYEDII NSNSASAIAM VPVVTTIK
//
