ID M3XGS4_LATCH Unreviewed; 200 AA.
AC M3XGS4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Interleukin-18 {ECO:0008006|Google:ProtNLM};
GN Name=LOC102356354 {ECO:0000313|Ensembl:ENSLACP00000021930.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000021930.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000021930.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the IL-1 family.
CC {ECO:0000256|ARBA:ARBA00010448}.
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DR EMBL; AFYH01006931; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006932; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006933; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006934; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006935; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006936; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01006937; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005987298.1; XM_005987236.2.
DR AlphaFoldDB; M3XGS4; -.
DR STRING; 7897.ENSLACP00000021930; -.
DR Ensembl; ENSLACT00000025435.1; ENSLACP00000021930.1; ENSLACG00000022302.1.
DR GeneID; 102356354; -.
DR GeneTree; ENSGT00390000001053; -.
DR HOGENOM; CLU_1345842_0_0_1; -.
DR InParanoid; M3XGS4; -.
DR OMA; QMQICFK; -.
DR OrthoDB; 4791062at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000022302; Expressed in pelvic fin.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR008996; IL1/FGF.
DR Pfam; PF00340; IL1; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
SQ SEQUENCE 200 AA; 23195 MW; 5EE6E397D1A23BA8 CRC64;
MSSETSTDSQ ATETEMWLAF FNDDGLWFEE VSTDYESDAW KKYTSADVKI INACNQILVA
QLQREDELGL VFHDVPSRNI RRDGMEFTFQ YYKETKPKRG IPLVFLVKME NKTFYMYCDK
ESSHTVLRFK EGNAPADISD NENSLIFYQV AASTGSHKTM FKAAYEEGLY LAFEKQDNLN
KLVLKRVNDE VDETATFRCQ
//
