ID M3XHX3_LATCH Unreviewed; 303 AA.
AC M3XHX3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Calcium homeostasis modulator 3 {ECO:0008006|Google:ProtNLM};
GN Name=LOC102354918 {ECO:0000313|Ensembl:ENSLACP00000022329.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022329.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000022329.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CALHM family.
CC {ECO:0000256|ARBA:ARBA00008497}.
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DR EMBL; AFYH01243208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01243209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01243210; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_014354052.1; XM_014498566.1.
DR AlphaFoldDB; M3XHX3; -.
DR STRING; 7897.ENSLACP00000022329; -.
DR Ensembl; ENSLACT00000026692.1; ENSLACP00000022329.1; ENSLACG00000022571.1.
DR GeneID; 102354918; -.
DR KEGG; lcm:102354918; -.
DR eggNOG; ENOG502QRUK; Eukaryota.
DR GeneTree; ENSGT01030000234610; -.
DR HOGENOM; CLU_069286_0_0_1; -.
DR InParanoid; M3XHX3; -.
DR OrthoDB; 5296902at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000022571; Expressed in muscle tissue.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR029569; CALHM.
DR PANTHER; PTHR32261; CALCIUM HOMEOSTASIS MODULATOR PROTEIN; 1.
DR PANTHER; PTHR32261:SF7; CALCIUM HOMEOSTASIS MODULATOR PROTEIN 3; 1.
DR Pfam; PF14798; Ca_hom_mod; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 303 AA; 34731 MW; 4EEE6424550E2CF4 CRC64;
MDRLLHSFQS SSGSLMNVLC AILALTSLGI YKSFKFICPC LPGGFNMLYG LGFMFVPPGI
FLFCGLIANK HLQLMLEEWV RPTGRRNKNP AIIRGFFFAS ITRSLVAPIV WILLSLMDGK
GPICAFSDSI NPEQFKGLDN ITAVDLYLLL SKVPCKTDPL IKRFPSARAV SRYIKAWSQS
IGWTIVLVAI MLAALARILK PCFRNETALQ NHYWSNYLDM EEKLFHKTCC MENYAFARKY
IARFFRSMNT DAQSQLRPVL DEDDYQGNMM DLEQLDALLQ SWHSNKPPLD VNLIYDRYRM
EYL
//
