ID M3XI78_LATCH Unreviewed; 561 AA.
AC M3XI78;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
GN Name=CUX1 {ECO:0000313|Ensembl:ENSLACP00000022434.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022434.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000022434.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC -!- SIMILARITY: Belongs to the CASP family.
CC {ECO:0000256|ARBA:ARBA00006415}.
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DR EMBL; AFYH01014584; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014586; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014588; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014589; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014591; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014592; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01014593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XI78; -.
DR Ensembl; ENSLACT00000025484.1; ENSLACP00000022434.1; ENSLACG00000017710.2.
DR GeneTree; ENSGT00940000159751; -.
DR HOGENOM; CLU_579474_0_0_1; -.
DR OMA; FAGYCFA; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000017710; Expressed in muscle tissue and 6 other cell types or tissues.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR012955; CASP_C.
DR PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR PANTHER; PTHR14043:SF15; SIMILAR TO CCAAT DISPLACEMENT PROTEIN ISOFORM B; 1.
DR Pfam; PF08172; CASP_C; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 502..523
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 305..526
FT /note="CASP C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08172"
FT COILED 1..237
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 388..436
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 561 AA; 64273 MW; 534F83D1CF5DE175 CRC64;
MHDIETENQK LRETLEEYNK EFAEVKNQEV TIKALKEKIR EYEQTLKNQA ENIALEKEQK
LQNDFAEKER KLQETQMSMA SKLQETEHKV QVAQTALETT QAELFDLKTK YDEEITAKAD
EIEMIMTDLE RANQRAEAAQ REAETLQEQL SSANKSLQLA TQIQKAPDVE QAIEVLTRSS
LEVELTAKER EIAQLVEDVQ RLQASLTKLR ENSASQILQL EQQLSAKNST LKQLEEKLKG
QSDYEEVKKE LNILKSMEYA PSESSGTQDA SKPLEVLLLE KNRALQSENA TLRITNNDLS
ARCTELQHQF TEAVTTTGVQ KELIAKLEHD LSTIQSMSSL QRPDAEGADV VSSLENIPQP
IKEATALFYG APPSPPPNLP QGQVDSLLSI ISSQRERFRA RNQELEVENR MMQQTMQALQ
SELDTLRADN IKLYEKIKFL QSYPGRGGSS DDTELRYSSQ YEERLDPFSS FSRKERQRKY
LSLSPWDKAT LSMGRVILSN KMARTITFFY TLLLHCLVFL VLYKTAWSES VGRDCAAFCA
KKYADHLHRF HENNDNGDMW Q
//
