ID M3XII1_LATCH Unreviewed; 1011 AA.
AC M3XII1;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Ataxin 2 like {ECO:0000313|Ensembl:ENSLACP00000022537.1};
GN Name=ATXN2L {ECO:0000313|Ensembl:ENSLACP00000022537.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022537.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000022537.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ataxin-2 family.
CC {ECO:0000256|ARBA:ARBA00007503}.
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DR EMBL; AFYH01166032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166033; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166034; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166037; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166039; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01166040; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006005921.1; XM_006005859.2.
DR AlphaFoldDB; M3XII1; -.
DR STRING; 7897.ENSLACP00000022537; -.
DR Ensembl; ENSLACT00000024901.1; ENSLACP00000022537.1; ENSLACG00000006023.2.
DR GeneID; 102360058; -.
DR CTD; 11273; -.
DR eggNOG; KOG2375; Eukaryota.
DR GeneTree; ENSGT00940000157795; -.
DR InParanoid; M3XII1; -.
DR OMA; ASFTMQG; -.
DR OrthoDB; 4269134at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000006023; Expressed in post-anal tail muscle and 6 other cell types or tissues.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR InterPro; IPR009818; Ataxin-2_C.
DR InterPro; IPR045117; ATXN2-like.
DR InterPro; IPR009604; LsmAD_domain.
DR InterPro; IPR047575; Sm.
DR InterPro; IPR025852; SM_dom_ATX.
DR PANTHER; PTHR12854; ATAXIN 2-RELATED; 1.
DR PANTHER; PTHR12854:SF8; ATAXIN-2-LIKE PROTEIN; 1.
DR Pfam; PF06741; LsmAD; 1.
DR Pfam; PF07145; PAM2; 1.
DR Pfam; PF14438; SM-ATX; 1.
DR SMART; SM01272; LsmAD; 1.
DR PROSITE; PS52002; SM; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 85..162
FT /note="Sm"
FT /evidence="ECO:0000259|PROSITE:PS52002"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 280..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 602..673
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 794..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..318
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 346..366
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..397
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..558
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..668
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..811
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 812..846
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 847..891
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1011 AA; 107874 MW; DA4DB9C0AF0B2A59 CRC64;
MLKQPPQQSG RKPAGGPGGS PAAAGGGTNP PTANSSSNSS AAAANGTVSP VTGLANSRPT
AGRGRSMGKG PSQSPVFEGV YSNSRMLHFL TAVVGSTCDV KVRNGAVYEG IFKTLSSKFE
LAVDAVHRKN PDQIVGPKRE DIIDTMIFKH SDVVMVHFKN IDLNYATKDR FTDSAIANNS
KVNGEHKEKV LQRWEGGDSN SDDYDLESDM SNGWDPNDMF KYNEENYGVK TTYDKSLSLY
TIPLEKDNSD EFRQREARAT QLAREIESNP QYRMRIAMEN DDGKTEEEKH SAIVRAVSDR
DSPNIVSRET KHNPLPQRAR EGSRGGMRSS SSRGGRPGSG SLPPRGSSHH PETSSSPVQE
QRVINGGPSR MSPKAQRPMR GPKPLSTPSS QRPVEVSTTP PAAAVTRIYP PRSPKSGSTP
PSVSSQDSPS GSAAPSAPTS PPEPRPCVET AATTASPNPP SPKTVAPTPL FTVDVKEILA
AGGKDPMRPP DTSGPPEGIR PAAKEPPSEH KRNQIEELKK FGEDFRLPPG STPDLGVDTL
PSRPKEGGES KPKEKLPSSN TADAETTTEP GAVAVQKPST EAGESKEDKA VAVVAAVVTT
LERTDRQAQA ASPLSKGEAE DKEAPMSDQV KKSTLNPNAK EFNPLKPMLP VNKPTSTPTP
PRPQTLPSPS ISMPVQGGMY NQYISYVHMN PAVQGPQMYQ YAVSTSVPLQ QGKYRGAKGS
VPPQRSDQHH PTSAPPIMQA AAAAGPPLVA APYSPSFIQY NAQQFTSQPA MMQAMTHYPS
QAVYAPMIQS NPRMMSGAHP QAIVSSSTPQ YPPPEQANPQ AMYPPVPQPY PHHTGPLHPH
PPQPATTPTG TQQQAQQAAP SPVQHQGAQP THLGSGQPQQ SLYHTTTLTP TPPSITPGPN
TQSPQSSFQQ PVYAIHAHQQ LQHGYTNMAH LTQAHVQSGM AAGPGHHGAS HHAQVMLLHA
PQTHGGPPQS AVPHSGVPPI SASTPTHYTY IGHHQVQPHP SQQLSFHPQG N
//
