ID   M3XIP0_LATCH            Unreviewed;       832 AA.
AC   M3XIP0;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Regulatory factor X1 {ECO:0000313|Ensembl:ENSLACP00000022596.1};
GN   Name=RFX1 {ECO:0000313|Ensembl:ENSLACP00000022596.1};
OS   Latimeria chalumnae (Coelacanth).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Coelacanthiformes; Coelacanthidae; Latimeria.
OX   NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022596.1, ECO:0000313|Proteomes:UP000008672};
RN   [1] {ECO:0000313|Proteomes:UP000008672}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA   Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA   MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT   "The draft genome of Latimeria chalumnae.";
RL   Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLACP00000022596.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AFYH01054552; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01054553; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01054554; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AFYH01054555; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; M3XIP0; -.
DR   STRING; 7897.ENSLACP00000022596; -.
DR   Ensembl; ENSLACT00000025246.1; ENSLACP00000022596.1; ENSLACG00000022433.1.
DR   eggNOG; KOG3712; Eukaryota.
DR   GeneTree; ENSGT01050000244879; -.
DR   HOGENOM; CLU_010393_1_0_1; -.
DR   InParanoid; M3XIP0; -.
DR   OMA; CCLEDER; -.
DR   Proteomes; UP000008672; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003150; DNA-bd_RFX.
DR   InterPro; IPR039779; RFX-like.
DR   InterPro; IPR007668; RFX1_trans_act.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12619:SF23; MHC CLASS II REGULATORY FACTOR RFX1; 1.
DR   PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR   Pfam; PF04589; RFX1_trans_act; 1.
DR   Pfam; PF02257; RFX_DNA_binding; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51526; RFX_DBD; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT   DOMAIN          292..367
FT                   /note="RFX-type winged-helix"
FT                   /evidence="ECO:0000259|PROSITE:PS51526"
FT   REGION          769..832
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        776..792
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   832 AA;  92691 MW;  9C504937421A5D61 CRC64;
     MKILTLMDNF VIVSVSLPLQ RSVVQTTPQT PKAGAVQQLT VQGLQQVHVT QENTVSQSSS
     ATKEDQIVGH PQSSECSIET EQLADYQPSS PEHRVQYLHM LPSTSEQRVE QLLQVVPQQV
     LVPQPKVVIE QIPLLPTLPS SPKQRVKVQR VPQVLVFGTA ATALKVQQLQ QVSVQHVYQN
     QVQYVEGGDA SYTASTIRSG TYPYTETPLY TQTTGANYYE SQGTPTQVST PVTSQNVASS
     GSVPMYVSGG QIVANPGGGG GGGAGTYVIQ GGYMLSSSSQ SYSHTTRASP ATVQWLLDNY
     ETAEGVSLPR STLYCHYLLH CQEQKLEPVN AASFGKLIRS VFMGLRTRRL GTRGNSKYHY
     YGLRIKANSP LLRLMEDQQH LAMRQQPFSQ KQRLKPIQKV EGMTNGMAVG QQQGGGLSDI
     SAQVQQYQQF LDATRALPEF ADIDLQGKSL PEGITLEHIK AFQLLYREHC EAIVDVMINL
     QFTLVETLWK TFWRYNSSQP TDTSPLAVHD DAEKRLPKSC LVILSKYDPV LKWSKDCDNM
     LYQGLVEILI PDVLRPIPSA LTQAIRNFAK SLESWLTNAM MNIPEEMVRV KVAAASAFAQ
     TLRRYTSLNH LAQAARAVLQ NTAQINQMLS DLNRVDFANV QEQASWVCRC EDGVVQRLEQ
     DFKMTLQQQN SLEQWASWLD GVVTQVLKPH QGSPSFPKAA KLFLLKWSFY SSMVIRDLTL
     RSAASFGSFH LIRLLYDEYM YFLIEHRVAQ AKGETPIAVM GEFANLGRSL NPLDPDKEEE
     EEEEEESDED SQQDISLISS ESATLVPESM EPPAKIPRTD NRGIFVQAPP SN
//