ID M3XJA3_LATCH Unreviewed; 146 AA.
AC M3XJA3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Cytochrome b5 type B {ECO:0000313|Ensembl:ENSLACP00000022809.1};
GN Name=CYB5B {ECO:0000313|Ensembl:ENSLACP00000022809.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000022809.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000022809.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family.
CC {ECO:0000256|ARBA:ARBA00038168, ECO:0000256|RuleBase:RU362121}.
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DR EMBL; AFYH01175253; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175255; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175256; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175257; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01175261; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_006006811.1; XM_006006749.2.
DR AlphaFoldDB; M3XJA3; -.
DR STRING; 7897.ENSLACP00000022809; -.
DR Ensembl; ENSLACT00000025842.1; ENSLACP00000022809.1; ENSLACG00000005062.2.
DR GeneID; 102354359; -.
DR KEGG; lcm:102354359; -.
DR eggNOG; KOG0537; Eukaryota.
DR GeneTree; ENSGT00940000155584; -.
DR HOGENOM; CLU_102602_3_3_1; -.
DR InParanoid; M3XJA3; -.
DR OMA; WTNFLIP; -.
DR OrthoDB; 2712490at2759; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000005062; Expressed in muscle tissue and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR018506; Cyt_B5_heme-BS.
DR PANTHER; PTHR19359; CYTOCHROME B5; 1.
DR PANTHER; PTHR19359:SF118; CYTOCHROME B5 TYPE B; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR PRINTS; PR00363; CYTOCHROMEB5.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS00191; CYTOCHROME_B5_1; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|RuleBase:RU362121};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|RuleBase:RU362121};
KW Membrane {ECO:0000256|RuleBase:RU362121};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362121};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672};
KW Transmembrane {ECO:0000256|RuleBase:RU362121};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362121}.
FT TRANSMEM 118..140
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362121"
FT DOMAIN 19..95
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 146 AA; 16467 MW; 6F76B509E56D5C4F CRC64;
MVEENGCPVQ EPESGPEPGN FLRMEEVKKH NSCKDTWMVI HDKVYDITRF LEEHPGGEEV
LFEQAGGDAT ESFEDVGHSV DAREMLTQYY IGELHPNDCK TANSKDASVT TSSSQSSWWM
SWLIPAIAVG ILGLMYRYYL VENKSS
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