ID M3XKC8_LATCH Unreviewed; 707 AA.
AC M3XKC8;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=DAB adaptor protein 2 {ECO:0000313|Ensembl:ENSLACP00000023184.1};
GN Name=DAB2 {ECO:0000313|Ensembl:ENSLACP00000023184.1};
OS Latimeria chalumnae (Coelacanth).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Coelacanthiformes; Coelacanthidae; Latimeria.
OX NCBI_TaxID=7897 {ECO:0000313|Ensembl:ENSLACP00000023184.1, ECO:0000313|Proteomes:UP000008672};
RN [1] {ECO:0000313|Proteomes:UP000008672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wild caught {ECO:0000313|Proteomes:UP000008672};
RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D.,
RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.;
RT "The draft genome of Latimeria chalumnae.";
RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLACP00000023184.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AFYH01110978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110979; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110980; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110981; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110982; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110983; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110984; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110985; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110986; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AFYH01110987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XKC8; -.
DR Ensembl; ENSLACT00000025252.1; ENSLACP00000023184.1; ENSLACG00000013028.2.
DR GeneTree; ENSGT00940000155567; -.
DR HOGENOM; CLU_020747_1_0_1; -.
DR Proteomes; UP000008672; Unassembled WGS sequence.
DR Bgee; ENSLACG00000013028; Expressed in pelvic fin and 6 other cell types or tissues.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR CDD; cd01215; PTB_Dab; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR048559; DAB1/2_SBM.
DR InterPro; IPR048561; Dab_PTB.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR PANTHER; PTHR47695:SF5; DISABLED HOMOLOG 2; 1.
DR PANTHER; PTHR47695; PID DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF21792; DAB2_SBM; 1.
DR SMART; SM00462; PTB; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS01179; PID; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Reference proteome {ECO:0000313|Proteomes:UP000008672}.
FT DOMAIN 39..149
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 351..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 610..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..707
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..576
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 707 AA; 76794 MW; C9B41244C954FD75 CRC64;
MSTEVESNTI NQADMSPSKK EKKKGSEKTD EFLLARFRGD GIRYKAKLIG IDDVPEARGD
KMSQDSMMKL KGMAVAARSQ GQHKQKIWLN ISLSGIKIID EKTGVIEHEH PVNKISFIAR
DVTDNRAFGY ICGAEGQHQF FAIKTAQQGV DQTDLFGDMS TPPDLNLPTE SKDILLLDLT
TEIDTNQNCV KRNPFFENGD TSCSTLAMPS SQTCFSPENP FSSNLSFFPA PNPDPFSDDP
FTKADQSVYA KSVNSLHTTN QNKEQFNHYL NGSMVIGDND FFGQQFDQIS NRTGKPPKSN
DPWPYENKLE KSTSWTENEM MEEQNRFLNK APQNPFVESY IKALPLQNGL MQDSQSNSSG
KMDTLQSQTS DSITISPPPQ SAKPGRSRRN VKSPSNDLVG SDFTPIAAAN QMTHPVQSIP
LQNNPMDLFN ATALSTTTSL GGLGGLSGGA LQTTSWGPQP SAFPQPPPVP AGTVMITQPT
PFRQPGVFNA PSSPGWGQPT LFGAPSQSQH PNPWGPAAPV QPGSWVQPVP TANPFQTNMF
TSSGPMAQPD PILMASSSPT IPSATPPQPP PRPVPQKEVL RPERDAFTAL DPLGDKEKKK
VKDMFKDFQL AKPPAVPARR AEQQQVPGTS GAFSSYFTSK VGIAQEAADF DDYDINQLSD
KTNEPPKPAP RQNAPPAQSL FDDPFGTNPF GGPTAAGSSD PFGNPFA
//
