ID M3XMJ4_MUSPF Unreviewed; 967 AA.
AC M3XMJ4;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Catenin delta 1 {ECO:0000313|Ensembl:ENSMPUP00000000294.1};
DE SubName: Full=Catenin delta-1 isoform X1 {ECO:0000313|RefSeq:XP_004777664.1, ECO:0000313|RefSeq:XP_012903943.1};
GN Name=CTNND1 {ECO:0000313|Ensembl:ENSMPUP00000000294.1,
GN ECO:0000313|RefSeq:XP_004777664.1, ECO:0000313|RefSeq:XP_012903943.1,
GN ECO:0000313|RefSeq:XP_012903944.1, ECO:0000313|RefSeq:XP_012903945.1,
GN ECO:0000313|RefSeq:XP_012903946.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000000294.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000000294.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004777664.1, ECO:0000313|RefSeq:XP_012903943.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004777664.1,
RC ECO:0000313|RefSeq:XP_012903943.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the beta-catenin family.
CC {ECO:0000256|ARBA:ARBA00005462}.
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DR EMBL; AEYP01091614; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01091615; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01091616; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01091617; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01091618; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01091619; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004777664.1; XM_004777607.3.
DR RefSeq; XP_012903943.1; XM_013048489.2.
DR RefSeq; XP_012903944.1; XM_013048490.2.
DR RefSeq; XP_012903945.1; XM_013048491.2.
DR RefSeq; XP_012903946.1; XM_013048492.2.
DR RefSeq; XP_012903947.1; XM_013048493.1.
DR STRING; 9669.ENSMPUP00000000294; -.
DR Ensembl; ENSMPUT00000000298.1; ENSMPUP00000000294.1; ENSMPUG00000000296.1.
DR GeneID; 101691593; -.
DR KEGG; mpuf:101691593; -.
DR CTD; 1500; -.
DR eggNOG; KOG1048; Eukaryota.
DR GeneTree; ENSGT00940000156045; -.
DR HOGENOM; CLU_009111_1_0_1; -.
DR OMA; GDQMSYP; -.
DR OrthoDB; 5473239at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0016342; C:catenin complex; IEA:Ensembl.
DR GO; GO:0009986; C:cell surface; IEA:Ensembl.
DR GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030496; C:midbody; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0045296; F:cadherin binding; IEA:Ensembl.
DR GO; GO:0140311; F:protein sequestering activity; IEA:Ensembl.
DR GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
DR GO; GO:0044331; P:cell-cell adhesion mediated by cadherin; IEA:Ensembl.
DR GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR GO; GO:0099072; P:regulation of postsynaptic membrane neurotransmitter receptor levels; IEA:Ensembl.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR028435; Plakophilin/d_Catenin.
DR PANTHER; PTHR10372:SF6; CATENIN DELTA-1; 1.
DR PANTHER; PTHR10372; PLAKOPHILLIN-RELATED; 1.
DR Pfam; PF00514; Arm; 4.
DR SMART; SM00185; ARM; 7.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715}.
FT REPEAT 408..445
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 451..494
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 710..747
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 628..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 855..872
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 873..888
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 911..925
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 967 AA; 108036 MW; D7F3F70A56007E75 CRC64;
MDDSEVESTA SILASVKEQE AQFEKLTRAL EEERRHVSAQ LERVRVSPQD ANPLMANGTL
TRRHQNGRFV GDADLERQKF SDLKLNGPQD HSHLVYSTIP RMQEPGQIVG TYTEEDPEGA
MSVVSVETSD DGTTRRTETT VKKVVKTVTT RTVQPVPVGP DGLPVDASSV SNNYIQTLGR
DFRKNGNGGP GPYVGQAGTA TLPRNFHYPP DGYSRHYEDG YPSSSDNYGS LSRVTRIEER
YRPSMEGYRA PSRQDVYGPQ PQVRVGGSSV DLHRFHPEPY GLEDDQRSMG YDDLDYGMMS
DYGTARRTGT PSDPRRRLRS YEDMIGEEVP SDQYYWAPLA QHERGSLASL DSLRKGGPPP
HNWRQPELPE VIAMLGFRLD AVKSNAAAYL QHLCYRNDKV KTDVRKLKGI PVLVGLLDHP
KKEVHLGACG ALKNISFGRD QDNKIAIKNC DGVPALVRLL RKARDMDLTE VITGTLWNLS
SHDSIKMEIV DHALHALTDE VIIPHSGWER EPNEDCKPRH IEWESVLTNT AGCLRNVSSE
RSEARRKLRE CDGLVDALIF IVQAEIGQKD SDSKLVENCV CLLRNLSYQV HREIPQAERY
QEAPPNVANN TGPHAASCFG AKKGKDEWFS RGKKPTEDPA NDTVDFPKRT SPARGYELLF
QPEVVRIYIS LLKESKTPAI LEASAGAIQN LCAGRWTYGR YIRSALRQEK ALSAIADLLT
NEHERVVKAA SGALRNLAVD ARNKELIGKH AIPNLVKNLP GGQPSSSQNF SEDTVVSLLN
TINEVIAENL EAAKKLRETQ GIEKLVLINK SGNRSEKEVR AAALVLQTIW GYKELRKPLE
KEGWKKSDFQ VNLNNASRSQ SSHSYDDSTL PLIDRNQKTD KKPDREEIQM SSMGSNTKSL
DNNYSTLNER GDHNRTLDRS GDLGEMEPLK GTPLMQDEGQ ESLEEELDVL VLDDEGDQVS
YPSMQKI
//
