ID   M3XNH3_MUSPF            Unreviewed;      1096 AA.
AC   M3XNH3;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=TBC1 domain family member 9B {ECO:0000313|Ensembl:ENSMPUP00000000623.1};
GN   Name=TBC1D9B {ECO:0000313|Ensembl:ENSMPUP00000000623.1};
OS   Mustela putorius furo (European domestic ferret) (Mustela furo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Mustelinae; Mustela.
OX   NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000000623.1};
RN   [1] {ECO:0000313|Ensembl:ENSMPUP00000000623.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAR-2023) to UniProtKB.
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DR   EMBL; AEYP01047773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEYP01047774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_012915140.1; XM_013059686.1.
DR   AlphaFoldDB; M3XNH3; -.
DR   STRING; 9669.ENSMPUP00000000623; -.
DR   Ensembl; ENSMPUT00000000635.1; ENSMPUP00000000623.1; ENSMPUG00000000629.1.
DR   eggNOG; KOG4347; Eukaryota.
DR   GeneTree; ENSGT00940000158554; -.
DR   HOGENOM; CLU_003535_0_1_1; -.
DR   InParanoid; M3XNH3; -.
DR   OMA; CTGEVPT; -.
DR   OrthoDB; 3034081at2759; -.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd13351; PH-GRAM1_TCB1D9_TCB1D9B; 1.
DR   CDD; cd13354; PH-GRAM2_TCB1D9_TCB1D9B; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   Gene3D; 1.10.8.270; putative rabgap domain of human tbc1 domain family member 14 like domains; 1.
DR   Gene3D; 1.10.10.750; Ypt/Rab-GAP domain of gyp1p, domain 1; 1.
DR   Gene3D; 1.10.472.80; Ypt/Rab-GAP domain of gyp1p, domain 3; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR000195; Rab-GAP-TBC_dom.
DR   InterPro; IPR035969; Rab-GAP_TBC_sf.
DR   InterPro; IPR036014; TCB1D9/TCB1D9B_PH-GRAM1.
DR   InterPro; IPR036017; TCB1D9/TCB1D9B_PH-GRAM2.
DR   PANTHER; PTHR47666; PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC; 1.
DR   PANTHER; PTHR47666:SF3; TBC1 DOMAIN FAMILY MEMBER 9B; 1.
DR   Pfam; PF02893; GRAM; 2.
DR   Pfam; PF00566; RabGAP-TBC; 1.
DR   SMART; SM00568; GRAM; 2.
DR   SMART; SM00164; TBC; 1.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   SUPFAM; SSF47923; Ypt/Rab-GAP domain of gyp1p; 2.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50086; TBC_RABGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT   DOMAIN          365..552
FT                   /note="Rab-GAP TBC"
FT                   /evidence="ECO:0000259|PROSITE:PS50086"
FT   DOMAIN          743..771
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          280..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          803..843
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          911..1000
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..304
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        805..843
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1096 AA;  122664 MW;  A4F52D65575EAEC6 CRC64;
     MRKQFGMPEG EKLVNYYSCS YWKGRVPRQG WLYLSVNHLC FYSFLLGKEV SLVVQWVDVT
     RLEKNATLLF PESIRVDTRD QELFFSMFLN IGETFKLMEQ LANLAMRQLL DSEGFLEEKA
     LPRPTRPHRN ISALKRDLDA RAKNECYRAT FRLPRDERLD GHTGCTLWTP FNKLHIPGQM
     FISSNYICFA SKEEDACHLI IPLREVTIVE KADSSSVLPS PLSISTKSKM TFLFANLKDR
     DFLVQRISDF LQKMPSKQPG GSSGGRKAST TDAALEHPLA PAEATDQPSP TTPLGGRQGS
     SVQEAPTASQ GLLKLFQGNS PMEDLGAKGA KEKMKEESWD IHFFEYGRGV CMYRTAKTRE
     LVLKGIPESL RGELWLLFSG AWNEMVTHPG YYAELVEKSM GKYSLATEEI ERDLHRSMPE
     HPAFQNELGI AALRRVLTAY AFRNPTIGYC QAMNIVTSVL LLYGSEEEAF WLLVALCERM
     LPDYYNTRVV GALVDQGIFE ELTRDFLPQL SEKMQDLGVI SSISLSWFLT LFLSVMPFES
     AVVIVDCFFY EGIKVILQVA LAILDANMEQ LLGCGDEGEA MTVLGRYLDN VVNKQSVSPP
     IPHLHALLTS GDDPPAEVDI FDLLKVSYEK FSSLRADDIE QMRFKQRLKV IQSLEDTAKR
     SVVRAIPGDI GFSIEELEDL YMVFKAKHLA SQYWGGSRPT AVRRDPSLPY LEQYRIDASQ
     FRELFTSLTP WACGAHTPVL AGRMFRLLDE NRDSLINFKE FVMGMSGMYH GDLTDKLKAL
     YKLHLPPALS PEEAESALEA THYFTEDSSS EETLRQEEQE RGGNEDSQEK RGEEKGTSPP
     DYRHYLRLWA KEKEVQKETI KDLPKMNQEQ FIELCKTLYN MFSEDPMEQA LYHAIATVAS
     LLLRIGEVGK KFSAPPGRKP RAGAAEEDEP PAPDPTQDPA LELQPPAAGD PQAKAGGDTH
     LGKAPQETQV VGDAGSGEGR GSPSQLLSDD ETKDDMSMSS YSVVSTGSLQ CEDLADDTVL
     VGAEARGPPA PTRGGGTVDT DWCISFEQIL ASILTESVLV NFFEKRVDIG LKIKDQKKVE
     RQFSTSSDLE QSGVSG
//