ID M3XNJ2_MUSPF Unreviewed; 1362 AA.
AC M3XNJ2;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Spermatogenesis associated 13 {ECO:0000313|Ensembl:ENSMPUP00000000642.1};
GN Name=SPATA13 {ECO:0000313|Ensembl:ENSMPUP00000000642.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000000642.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000000642.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
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DR EMBL; AEYP01083752; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083753; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083755; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083756; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083757; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083758; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083759; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01083760; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9669.ENSMPUP00000000642; -.
DR Ensembl; ENSMPUT00000000654.1; ENSMPUP00000000642.1; ENSMPUG00000000648.1.
DR eggNOG; KOG3519; Eukaryota.
DR GeneTree; ENSGT00940000154103; -.
DR HOGENOM; CLU_008436_0_0_1; -.
DR InParanoid; M3XNJ2; -.
DR OMA; NVTEVAW; -.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0030175; C:filopodium; IEA:Ensembl.
DR GO; GO:0030027; C:lamellipodium; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0032587; C:ruffle membrane; IEA:Ensembl.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:Ensembl.
DR GO; GO:0016477; P:cell migration; IEA:Ensembl.
DR GO; GO:0046847; P:filopodium assembly; IEA:Ensembl.
DR GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR CDD; cd01224; PH_Collybistin_ASEF; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11973; SH3_ASEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR47544; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4; 1.
DR PANTHER; PTHR47544:SF2; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 9; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1362
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004043897"
FT DOMAIN 857..916
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 950..1134
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1165..1271
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 64..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 368..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 510..727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 919..949
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..564
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 925..942
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1362 AA; 151712 MW; F465E4F5D7E8B6ED CRC64;
MFGRILAALY FSPLLFCKIS RFVNPTTPRE TQELTWPYQV KVQTGDFHLS VLFQLQAVAT
SEEPDVHSRC ESQAGSSLGD EGLHPGPVDT DVQVGLNPTA LWPRTHSPEN MTTAQNGHGQ
LAAIPCSVSD PKDPKMVTYP ACQNGGCSSS YCGEAEAQEA RLSPAKLMRL FSVSRKRTGT
NPERPRSMVL MGNSSTWNAL ASFRKMGSFK KLKSSVLQGI QNREASDVPR EDPPERDPGK
PISNGAAVGM QTSRCPNSGP ASDAPKAGPG GVSDCSDPEE ADDAFQRSTH RSRSIRRAYG
LGRISLLDGD KHPGSQNHVR PLAPGPQEPT VCEILVKDSE NNSIIYRKSK STDNLNFLKK
SSFKRKSTSN LMDLKGAQEK PAPRRTLSSS SADSEKFGGS ERRTKRWKSP LRAKDFDRVL
RFVSSATDAA WRKESPRSGA PSPGEASQRL QVHSRLHDAY SRRVSTSAER EWRRCAGAHA
GSGCGSPGAP SPRVDVDTAV FPLEAPGSWA AESARPCAAS ASSSPVAQDS EERRAGGPFT
FEAEQPLIPP RPTTPKPPSP HSPGAGSAAC PNSLSALSLS SVDSEERAEG PVTSRDSVQA
AYDKGREDSA GSHPQLSPHL ASGAEERREE VVTEESWRRD SSRDEERTES QRITRRKWGS
GRRARPRPLS DYGQLANRSL SIPEDSVAVD PQKEDTVEGD HLPNMASTDT TDQSDTADQS
AAVGCPKGSW RRRPISVIGG VSFYGNSPTE EIESLLTQPA ARPPVPAHRV LPYKAVSARF
RPFTFSQSTP IGLDRVGRRR QMRASNVSSD GGTESAALVD DNGSEEDYSY EDLCQANPRY
LQPGGEQLAI NELISDGSVV CAEALWDHVT MDDQELGFKA GDVIQVLEAS NKDWWWGRNE
DKEAWFPASF VRLRVNQEEL SENSSSTQGE EHEEDAGKNH HKHSESKHQM RTNVIQEIMN
TERVYIKHLK DICEGYIRQC RKHTGMFTVA QLATIFGNIE DIYKFQRKFL KDLEKQYNKE
EPHLSEIGSC FLQHQEGFAI YSEYCNNHPG ACAELSNLMK QGRYRHFFEA CRLLQQMIDI
AIDGFLLTPV QKICKYPLQL AELLKYTTPE HSDYNNIKAA YEAMKNVACL INERKRRLES
IDKIARWQVS IVGWEGLDIL DRSSELIHSG ELTKVTRHGK SQQRTFFLFD HQLVSCKKDL
LRRDVLYYRG RTDMDDVELV DLEDGRDKDW NLSVKNAFKL VSKTTDEVHL FCARKQEDKV
RWLQACEDER RRVREDREMG MEISENQKKL AMLNAQKAGH GKSKGYSGCP VAPPHQNLHP
LHQRHVTVPT SVPQQQVFAL AEPKRKPSLF WHTFNKLTPF KK
//
