ID M3XPP5_MUSPF Unreviewed; 748 AA.
AC M3XPP5;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=BTB domain and CNC homolog 1 {ECO:0000313|Ensembl:ENSMPUP00000001045.1};
DE SubName: Full=Transcription regulator protein BACH1 isoform X1 {ECO:0000313|RefSeq:XP_004757531.1, ECO:0000313|RefSeq:XP_012914284.1};
GN Name=BACH1 {ECO:0000313|Ensembl:ENSMPUP00000001045.1,
GN ECO:0000313|RefSeq:XP_004757531.1, ECO:0000313|RefSeq:XP_012914284.1,
GN ECO:0000313|RefSeq:XP_044941106.1, ECO:0000313|RefSeq:XP_044941107.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000001045.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000001045.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004757531.1, ECO:0000313|RefSeq:XP_012914284.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004757531.1,
RC ECO:0000313|RefSeq:XP_012914284.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AEYP01043042; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01043043; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01043044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004757531.1; XM_004757474.3.
DR RefSeq; XP_012914284.1; XM_013058830.2.
DR RefSeq; XP_044941106.1; XM_045085171.1.
DR RefSeq; XP_044941107.1; XM_045085172.1.
DR STRING; 9669.ENSMPUP00000001045; -.
DR Ensembl; ENSMPUT00000001066.1; ENSMPUP00000001045.1; ENSMPUG00000001053.1.
DR GeneID; 101687436; -.
DR KEGG; mpuf:101687436; -.
DR CTD; 571; -.
DR eggNOG; KOG3863; Eukaryota.
DR GeneTree; ENSGT00940000158923; -.
DR HOGENOM; CLU_015243_2_0_1; -.
DR OMA; RRSECPW; -.
DR OrthoDB; 382726at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0090575; C:RNA polymerase II transcription regulator complex; IEA:Ensembl.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0098531; F:ligand-activated transcription factor activity; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0006281; P:DNA repair; IEA:Ensembl.
DR CDD; cd18277; BTB_POZ_BACH1; 1.
DR CDD; cd14719; bZIP_BACH; 1.
DR Gene3D; 1.10.880.10; Transcription factor, Skn-1-like, DNA-binding domain; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR043321; bZIP_BACH.
DR InterPro; IPR004826; bZIP_Maf.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR008917; TF_DNA-bd_sf.
DR PANTHER; PTHR46105; AGAP004733-PA; 1.
DR PANTHER; PTHR46105:SF1; TRANSCRIPTION REGULATOR PROTEIN BACH1; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF03131; bZIP_Maf; 1.
DR SMART; SM00338; BRLZ; 1.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF47454; A DNA-binding domain in eukaryotic transcription factors; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50217; BZIP; 1.
DR PROSITE; PS00036; BZIP_BASIC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 34..100
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 566..624
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 287..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 579..613
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 287..302
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 82696 MW; 49078DFA9BAC37F0 CRC64;
MSLSEIAVFA YESSVHSTNV LLSLNDQRKK DVLCDVTVLV EGQRFRAHRS VLAACSSYLH
SRIVGQADAE LNITLPEEVT VKGFEPLIQF AYTAKLILNK DNVDEVCKCV EFLGVRDIEE
SCFQFLKFKF LDSTADQQEC LRKKCIPSHC QKADLKCSLL DQRDLEIDEV EEFLENKNVQ
TSQWKLHRYQ ANAKVSSPLQ DSASQTCESM CLEKDAALAL PSLCPKYRKF QKAFGTDRVR
TVESSVKDVQ ASSVQPNETP ENECLGRIQD CADLQVTLKC EESRLATEHE ETKKEDPASH
CPSEKSEVTP FPHNSSADPH GLYSLSLLHT YDQYGDLNFA GMQNTAVLTE KPLSGTEVKE
EKTFGESQDL HLKSDSGPRE DSSLASSDRS SVEREVAEHL AKGFWSDICS TDSSCQMQLS
PAVAKDGSEQ IYSQKRSECP WLGIRISESP EPGQRTFTTL SSVNCPFIST LSTEGCSSNL
EIGNVEYVSE PQQEPYPYAC VISLGDDSET DTEGDSEPCS AREQECEVKL PFNAQRIISL
SRNDFQSLLK MHKLTPEQLE CIHDIRRRSK NRIAAQRCRK RKLDCIQNLE SEIEKLQNEK
ESLLKERDHI LSTLGETKQN LTGLCQQVCK EAALSQEQIQ ILAKYSASDC PLSLLISEKE
KSTPDGERVL PSLLSLPEGP PAGPPTCEPS VCHPSAQSGG SAGSAPGQEP RAAASTAPEQ
AGLGEPCQPG GGISDFCQQM TDKCTTDE
//
