ID M3XQC9_MUSPF Unreviewed; 2465 AA.
AC M3XQC9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=SON DNA binding protein {ECO:0000313|Ensembl:ENSMPUP00000001279.1};
GN Name=SON {ECO:0000313|Ensembl:ENSMPUP00000001279.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000001279.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000001279.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
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DR EMBL; AEYP01043174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR STRING; 9669.ENSMPUP00000001279; -.
DR Ensembl; ENSMPUT00000001306.1; ENSMPUP00000001279.1; ENSMPUG00000001290.1.
DR eggNOG; ENOG502QPQ7; Eukaryota.
DR GeneTree; ENSGT00730000111141; -.
DR HOGENOM; CLU_230016_0_0_1; -.
DR InParanoid; M3XQC9; -.
DR OMA; NETEQCT; -.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0000281; P:mitotic cytokinesis; IEA:Ensembl.
DR GO; GO:0006397; P:mRNA processing; IEA:Ensembl.
DR GO; GO:0043066; P:negative regulation of apoptotic process; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR GO; GO:0048024; P:regulation of mRNA splicing, via spliceosome; IEA:Ensembl.
DR CDD; cd19870; DSRM_SON-like; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR032922; SON.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR46528; PROTEIN SON; 1.
DR PANTHER; PTHR46528:SF1; PROTEIN SON; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17069; RSRP; 1.
DR SMART; SM00358; DSRM; 1.
DR SMART; SM00443; G_patch; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50137; DS_RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 4: Predicted;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 2311..2357
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 2377..2447
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 23..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 79..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 371..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1220
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1240..1263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1519..1543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1768..2059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2206..2226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..127
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..150
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1178
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1787..1834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1848..1921
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1928..1951
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1964..2012
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2025..2049
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2465 AA; 266653 MW; 339EFC4EE814BFBE CRC64;
MATNIEQIFR SFVVSKFREI QQELSSGRSE GQLNGETNTP NEGNQAGDAA ASARSLPNEE
IVQKIEEVLS GVLDTELRYK PDLKEASRKS KCVSVQTDPT DEIPTKKSKK HKKHKNKKKK
KKKEKEKKYK RQPEESESKA KSHHDGNIDL ESDSFLKFDS EPSAVALEHP VRAFGLSETS
ESPAVVLEPP VVSMEVSEAH TLETLKPATK TAELSVASTS TISVQSEQSV AVTLESSMTK
ILDSFTTAPV PTTTVMLKSP EPAVTMSMEY QMKPMLKSLE TTPPEQSKVM LEPPVAKGLE
PSETLVLLSE IPTEVHPEPS TSTTMDFPES SATEGVRLPE QPVEVPSEIA DSSMTRPQEL
PELPKTTALE QPESSVASVM ELPGPPATSK PELQGPPVTP VLELPGPSAT PLPELPGPLS
TPVPELLGPP ATAVPELPGP SATSVPQLSQ ELPGLPAPSV GLEPPQEVPE PPVMAQELPG
LPAVTAAVEL PGQPAVTVAM ELTEQPVTTS ELEQPVGMTA VEHPGQPEVT TATGLLGQPE
AAMVLELPGQ PVATTALELP GQPSVTGVPE LPGLPSATRA LELSGQPVAT GALELPGQLM
ATGALEFSGQ SGAAGALELL GQPLATGVLE LPGQPGAPEL PGQPVATVAL EISVQSVVTT
ELSTMTVSQS LEVPSTTALE SYNTVAQELP TTLVGETSVT VGVDPLMAQE SHMLASNTME
THMLASNTMD SQMLASNTMD SQMLASNTMD SQMLATSSMD SQMLATSSMD SQMLATSSMD
SQMLATSSMD SQMLATSSMD SQMLATSSMD SQMLATSSMD SQMLATSSMD SQMLATSTMD
SQMLATSTMD SQMLATSSMD SQMLASGTMD SQMLASGTMD AQMLASGSMD AQMLASSTQD
SAMLGSKSPD PYRLAQDPYR LAQDPYRLGH DPYRLGHDAY RLGQDPYRLG HDPYRLTPDP
YRMSPRPYRI APRSYRIAPR PYRLAPRPLM LASRRSMMMS YAAERSMMSS YERSMMSYER
SMMSPMAERS MMSAYERSMM SAYERSMMSP MAERSMMSAY ERSMMSAYER SMMSPMADRS
MMSMSADRSM MSSYSAADRS MMSSYSAADR SMMSSYTADR SMMSMAADSY TDSYTDTYTE
AYMVPPLPPE EPPTMPPLPP EEPPMTPPLP PEEPPEGPAL PTEQSALTAE NTWPTEVPAL
PPEESVSLSE PSVSQSEISE PSALPANYSV SASDPSALAS EAAVTVPDPA LEPESSVTST
PVESAVVAEE HQVVPERAVT YMVSETTIMS AEPTVLASES SVMSETAETF DSMKASGHAS
EVSLSLLDPA AANPEASQST LELPAMAVSE LPAVAVPEPP TGTVPEPPAA AAVLEPPAVA
IPDPTAVAVS DPIAVAVPDT PAEGVPETLA LAESEHVTTP VPVVSALEPT VPVLEPAVSV
PQSNTVVSEP SVPVQEPTVI ISEPAVTVSE QTQVIPTEMV LESTPMILES SVVKGVNLLS
SDQNTAPEIG MQEIPMHSDE EPHAEGHLKN DPYESEHGTD TDLKTDNHFV AQEMEHNTAS
AASTGAVGEI GEGNILSIGE TKQCTVLDTC SSVSEADGGT LSSAGPLALE PDAVGTSKGI
EFAIASALGS VSNYDAEVSL TAQDTEHDMI ISTSPSGGSE ADIEGPLPAK DIHLDLPSNN
FINKDAEGPL SIKDCDQTLA VALSPKESSG EDKEIPLPTK EIQSDSGFSA TIDDINEADL
VRPLLPKDME RLTSLRAGIE GPLLPSEVER DKSAASPVVI SIPERASESS SEEKDDYEIF
VKVKDTHEKS KKNKNRDKGE KEKKRDSSLR SRSKRSKSSE HKSRKRTSES RSRARKRSSK
SKSHRSQTRS RSRSRRRRRS SRSRSKSRGR RSVSKEKRKR SPKHRSKSRE RKRKRSSSRD
NRKTVRARSR TPSRRSRSHT PSRRRRSRSV GRRSFSISPS RRSRTPSRRS RTPSRRSRTP
SRRSRTPSRR SRTPSRRSRT PSRRRRSRSV VRRRSFSISP VRLRRSRTPL RRRFSRSPIR
RKRSRSSERG RSPKRLTDLN KAQLLEIAKA NAAAMCAKAG VPLPPNLKPA PPPTIEEKVA
KKSGGATIEE LTEKCKQIAQ SKEDDDVIVN KPHVSDEEEE EPPFYHHPFK LSEPKPIFFN
LNIAAAKPTP PKSQVTLTKE FPVSSGSQHR KKEADSVYGE WVPVEKNGEE NKDDDNVFSS
NLPSEPVDIS TAMSERALAQ KRLSENAFDL EAMSMLNRAQ ERIDAWAQLN SIPGQFTGST
GVQVLTQEQL ANTGAQAWIK KDQFLRAAPV TGGMGAVLMR KMGWREGEGL GKNKEGNKEP
ILVDFKTDRK GLVAVGERAQ KRSGNFSAAM KDLSGKHPVS ALMEICNKRR WQPPEFLLVH
DSGPDHRKHF LFRVLINGSA YQPSFASPNK KHAKATAATV VLQAMGLVPK DLMANATCFR
SASRR
//
