ID M3XVB3_MUSPF Unreviewed; 1231 AA.
AC M3XVB3;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=PTPRF interacting protein alpha 3 {ECO:0000313|Ensembl:ENSMPUP00000003013.1};
GN Name=PPFIA3 {ECO:0000313|Ensembl:ENSMPUP00000003013.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000003013.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000003013.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01068254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; M3XVB3; -.
DR STRING; 9669.ENSMPUP00000003013; -.
DR Ensembl; ENSMPUT00000003074.1; ENSMPUP00000003013.1; ENSMPUG00000003043.1.
DR eggNOG; KOG0249; Eukaryota.
DR GeneTree; ENSGT01050000244900; -.
DR HOGENOM; CLU_006923_0_0_1; -.
DR InParanoid; M3XVB3; -.
DR OMA; LMMMCEV; -.
DR GO; GO:0001669; C:acrosomal vesicle; IEA:Ensembl.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0098831; C:presynaptic active zone cytoplasmic component; IEA:Ensembl.
DR GO; GO:0016081; P:synaptic vesicle docking; IEA:Ensembl.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF4; LIPRIN-ALPHA-3; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils}.
FT DOMAIN 875..941
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 997..1054
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 1078..1147
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1194..1231
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 39..123
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 256..423
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 452..500
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 199..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..679
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1211..1231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1231 AA; 137361 MW; 06F73F7E671989CA CRC64;
MMCEVMPTIS EDGRRGSALG PDEAGGELER LMVTMLTERE RLLETLREAQ DGLATAQLRL
RELGHEKDSL QRQLSIALPQ EFAALTKELN LCREQLLERE EEIAELKAER NNTRLLLEHL
ECLVSRHERS LRMTVVKRQA QSPGGVSSEV EVLKALKSLF EHHKALDEKV RERLRMALER
VAVLEEELEL SNQETLSLRE QLSRRRSGLE EPGKDGDGQP LANGLGPGGD SNRRTAELEE
ALERQRAEVC QLRERLAVLC RQMSQLEEEL GTAHRELGKA EEANAKLQRD LKEALAQRED
MEERITTLEK RYLSAQREAT SLHDANDKLE NELASKESLY RQSEEKSRQL AEWLDDAKQK
LQQTLQKAET LPEIEAQLAQ RVAALNKAEE RHGNFEERLR QLEAQLEEKN QELQRARQRE
KMNDDHNKRL SETVDKLLSE SNERLQLHLK ERMGALEEKN SLSEEIANMK KLQDELLLNK
EQLLAEMERM QMEIDQLRGR PPSSYSRSLP GSALELRYSQ APTLPSGAHL DPYGAGSGRA
GKRSRWSGVK DEPSKVPTQR QEWERSAPAG SMPPPFPGEL DGSDEEEAEG MFGAELLSPS
GQADVQTLAI MLQEQLEAIN KEIKLIQEEK ETTEQRAEEL ESRVSGSGLD SLGRYRSSCS
LPPSLTTSTL ASPSPPSSGH STPRLAPPSP AREGTDKAVS VLESHFASRP FCPQNHVPKE
EAGAPRGEGP AIPGDTPPPT PRSARLERMT QALALQAGSL EDGGPSRGRS AGTVDGMSLS
CSPSEGTPDS LHKAPKKKSI KSSIGRLFGK KEKGRMGPPG RDSSSLAGTP SDETLATDPL
GLAKLTGPGD KDRRNKRKHE LLEEACRQGL PFAAWDGPTV VSWLELWVGM PAWYVAACRA
NVKSGAIMAN LSDTEIQREI GISNPLHRLK LRLAIQEMVS LTSPSAPASS RTSTGNVWMT
HEEMESLTAT TKPETKEISW EQILAYGDMN HEWVGNDWLP SLGLPQYRSY FMESLVDARM
LDHLNKKELR GQLKMVDSFH RVSLHYGIMC LKRLNYDRKD LERRREESQT QIRDVMVWSN
ERVMGWVSGL GLKEFATNLT ESGVHGALLA LDETFDYSDL ALLLQIPTQN AQARQLLEKE
FSNLISLGTD RRLDEDSAKS FSRSPSWRKM FREKDLRGVT PDSAEMLPPN FRSAAAGALG
SPGLPLRKLQ PEGQTSGSSR ADGVSVRTYS C
//
