ID M3XWS9_MUSPF Unreviewed; 243 AA.
AC M3XWS9;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Fibroblast growth factor {ECO:0000256|RuleBase:RU049442};
DE Short=FGF {ECO:0000256|RuleBase:RU049442};
GN Name=FGF12 {ECO:0000313|Ensembl:ENSMPUP00000003529.1,
GN ECO:0000313|RefSeq:XP_004745329.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000003529.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000003529.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004745329.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004745329.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the heparin-binding growth factors family.
CC {ECO:0000256|ARBA:ARBA00007936, ECO:0000256|RuleBase:RU049442}.
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DR EMBL; AEYP01017380; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017382; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017383; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017385; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017388; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01017389; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004745329.1; XM_004745272.3.
DR STRING; 9669.ENSMPUP00000003529; -.
DR Ensembl; ENSMPUT00000003596.1; ENSMPUP00000003529.1; ENSMPUG00000003559.1.
DR GeneID; 101686612; -.
DR KEGG; mpuf:101686612; -.
DR CTD; 2257; -.
DR eggNOG; KOG3885; Eukaryota.
DR GeneTree; ENSGT00940000155929; -.
DR HOGENOM; CLU_081609_2_0_1; -.
DR OMA; HEIGDKA; -.
DR OrthoDB; 5348469at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR GO; GO:0008344; P:adult locomotory behavior; IEA:Ensembl.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:0050905; P:neuromuscular process; IEA:Ensembl.
DR GO; GO:0010765; P:positive regulation of sodium ion transport; IEA:Ensembl.
DR GO; GO:0098908; P:regulation of neuronal action potential; IEA:Ensembl.
DR CDD; cd00058; FGF; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR002209; Fibroblast_GF_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR11486; FIBROBLAST GROWTH FACTOR; 1.
DR PANTHER; PTHR11486:SF17; FIBROBLAST GROWTH FACTOR 12; 1.
DR Pfam; PF00167; FGF; 1.
DR PRINTS; PR00263; HBGFFGF.
DR PRINTS; PR00262; IL1HBGF.
DR SMART; SM00442; FGF; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
DR PROSITE; PS00247; HBGF_FGF; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 216..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..243
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 243 AA; 27399 MW; 773ED10B5BDD033C CRC64;
MAAAIASSLI RQKRQARESN SDRVSASKRR SSPSKDGRSL CERHVLGVFS KVRFCSGRKR
PVRRRPEPQL KGIVTRLFSQ QGYFLQMHPD GTIDGTKDEN SDYTLFNLIP VGLRVVAIQG
VKASLYVAMN GEGYLYSSDV FTPECKFKES VFENYYVIYS STLYRQQESG RAWFLGLNKE
GQIMKGNRVK KTKPSSHFVP KPIEVCMYRE PSLHEIGEKQ GRSRKSSGTP TMNGGKVVNQ
DST
//
