ID M3XXL7_MUSPF Unreviewed; 328 AA.
AC M3XXL7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Carbonic anhydrase-related protein 11 {ECO:0000256|ARBA:ARBA00041142};
DE AltName: Full=CA-RP XI {ECO:0000256|ARBA:ARBA00042748};
GN Name=CA11 {ECO:0000313|Ensembl:ENSMPUP00000003817.1,
GN ECO:0000313|RefSeq:XP_004767468.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000003817.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000003817.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004767468.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004767468.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Does not have a catalytic activity.
CC {ECO:0000256|ARBA:ARBA00002258}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEYP01068282; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004767468.1; XM_004767411.3.
DR STRING; 9669.ENSMPUP00000003817; -.
DR Ensembl; ENSMPUT00000003886.1; ENSMPUP00000003817.1; ENSMPUG00000003847.1.
DR GeneID; 101672286; -.
DR KEGG; mpuf:101672286; -.
DR CTD; 770; -.
DR eggNOG; KOG0382; Eukaryota.
DR GeneTree; ENSGT00940000162098; -.
DR HOGENOM; CLU_039326_7_0_1; -.
DR OMA; HKNQNAC; -.
DR OrthoDB; 49814at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:Ensembl.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR041878; Alpha_CARP_X/XI.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF93; CARBONIC ANHYDRASE-RELATED PROTEIN 11; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..328
FT /note="Carbonic anhydrase-related protein 11"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041198384"
FT DOMAIN 33..303
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
FT REGION 300..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 328 AA; 36172 MW; 07D60503EC7565C6 CRC64;
MGVAARLSVP RALVLWAALG AAAHIGPAPD PEDWWSYKDN LQGNFVPGPP FWGLVNAAWS
LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL YNTGRHVSFL PAPRPVVNVS
GGPLLYSHRL SELRLLFGAR DGAGSEHQIN HQGFSAEVQL IHFNQELYGN LSAASRGPNG
LAILSLFINV AGSSNPFLSR LLNRDTITRI SYKNDAYFLQ DLSLELLFPE SFGFITYQGS
LSTPPCSETV TWILIDRALN ITSLQMHSLR LLSQNPPSQI FQSLSGNGRP LQPLAHRALR
GNRDPRHPER RCRGPNYRLH VDGAPHGR
//
