ID M3XYM7_MUSPF Unreviewed; 86 AA.
AC M3XYM7;
DT 01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT 01-MAY-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Serine peptidase inhibitor, Kazal type 4 {ECO:0000313|Ensembl:ENSMPUP00000004178.1};
DE SubName: Full=Serine protease inhibitor Kazal-type 4 {ECO:0000313|RefSeq:XP_004765402.1};
GN Name=SPINK4 {ECO:0000313|Ensembl:ENSMPUP00000004178.1,
GN ECO:0000313|RefSeq:XP_004765402.1};
OS Mustela putorius furo (European domestic ferret) (Mustela furo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Mustelinae; Mustela.
OX NCBI_TaxID=9669 {ECO:0000313|Ensembl:ENSMPUP00000004178.1};
RN [1] {ECO:0000313|Ensembl:ENSMPUP00000004178.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (MAR-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_004765402.1}
RP IDENTIFICATION.
RC TISSUE=Brain {ECO:0000313|RefSeq:XP_004765402.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; AEYP01063275; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01063276; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AEYP01063277; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004765402.1; XM_004765345.3.
DR STRING; 9669.ENSMPUP00000004178; -.
DR MEROPS; I01.970; -.
DR Ensembl; ENSMPUT00000004253.1; ENSMPUP00000004178.1; ENSMPUG00000004212.1.
DR GeneID; 101686409; -.
DR KEGG; mpuf:101686409; -.
DR CTD; 27290; -.
DR eggNOG; KOG3649; Eukaryota.
DR GeneTree; ENSGT00530000064269; -.
DR HOGENOM; CLU_169765_2_0_1; -.
DR OMA; ECHLCLT; -.
DR OrthoDB; 2920086at2759; -.
DR Proteomes; UP000000715; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 3.30.60.30; -; 1.
DR InterPro; IPR002350; Kazal_dom.
DR InterPro; IPR036058; Kazal_dom_sf.
DR InterPro; IPR039932; Spink4-like.
DR PANTHER; PTHR21179:SF0; SERINE PROTEASE INHIBITOR KAZAL-TYPE 4; 1.
DR PANTHER; PTHR21179; SERINE-TYPE ENDOPEPTIDASE INHIBITOR; 1.
DR Pfam; PF00050; Kazal_1; 1.
DR SMART; SM00280; KAZAL; 1.
DR SUPFAM; SSF100895; Kazal-type serine protease inhibitors; 1.
DR PROSITE; PS00282; KAZAL_1; 1.
DR PROSITE; PS51465; KAZAL_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Protease inhibitor {ECO:0000313|RefSeq:XP_004765402.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000715};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..86
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041158443"
FT DOMAIN 31..86
FT /note="Kazal-like"
FT /evidence="ECO:0000259|PROSITE:PS51465"
SQ SEQUENCE 86 AA; 9488 MW; F24DA9236932379F CRC64;
MAVRSWMVAL AVAALLIVDR EMPVSATSLI SPRMPICEHM EESPVCSQTS NLVCGTDGVT
YDNECQICLI RLKTKQDIQI MKDGKC
//
